Results 1 to 10 of about 86,540 (189)

A plain language summary of what freedom from disease means to people with psoriasis according to doctors, nurses, and people with psoriasis [PDF]

open access: yesJournal of Comparative Effectiveness Research, 2023
What is this summary about? This summary presents findings from recent research involving people with psoriasis, based on an article originally published in the Journal of the European Academy of Dermatology and Venereology.
Ilse van Ee   +13 more
doaj   +2 more sources

The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint [PDF]

open access: yesCell Reports
Summary: The methyl donor S-adenosylmethionine (SAM) regulates many cellular processes. The N6-methyladenosine (m6A) methyltransferase METTL16 regulates the expression of the SAM synthetase MAT2A, but the consequences of this regulation are not well ...
Juliana N. Flaherty   +10 more
doaj   +2 more sources

Tofersen decreases neurofilament levels supporting the pathogenesis of the SOD1 p.D91A variant in amyotrophic lateral sclerosis patients [PDF]

open access: yesCommunications Medicine
Background Since the antisense oligonucleotide tofersen has recently become available for the treatment of amyotrophic lateral sclerosis (ALS) caused by mutations in SOD1, determining the causality of the over 230 SOD1 variants has become even more ...
Jochen H. Weishaupt   +13 more
doaj   +2 more sources

Author Correction: Targeting ferroptosis protects against experimental (multi)organ dysfunction and death [PDF]

open access: yesNature Communications
Samya Van Coillie   +28 more
doaj   +2 more sources

A L’ENVERS, À L’ENDROIT : Freud et le littéraire, à la source

open access: yesRelief: Revue Électronique de Littérature Francaise, 2010
Dans une lettre à Wilhelm Fliess datant de 1898 Freud donne pour la toute première fois le commentaire d’un texte littéraire. Il souligne l’analogie entre la nouvelle de Conrad Ferdinand Meyer, Die Richterin, et le roman familial de ses patients. On peut
Sjef Houppermans
doaj   +5 more sources

The Pivotal Role of Quality Technical Structures for Clinical Trials Oversight in the Achievement of Long-Term Capacity Strengthening Outcomes

open access: yesFrontiers in Medicine, 2022
BackgroundDevelopment of safe and efficacious medicines in many sub-Sahara African countries remains hampered due to fragmented health research infrastructure and ineffective regulatory oversight.
Solomon Owusu Sekyere   +10 more
doaj   +1 more source

Seed-produced anti-globulin VHH-Fc antibodies retrieve globulin precursors in the insoluble fraction and modulate the Arabidopsis thaliana seed subcellular morphology [PDF]

open access: yes, 2020
Key message Nanobody-heavy chain (VHH-Fc) antibody formats have the potential to immunomodulate even highly accumulating proteins and provide a valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.
Altmann, Friedrich   +7 more
core   +2 more sources

Real-Time Cost Minimization of Fog Computing in Mobile-Base-Station Networked Disaster Areas

open access: yesIEEE Open Journal of the Computer Society, 2021
The use of big data has led to many technologies that were previously thought to be impossible. We are now able to analyze the spread of a disaster automatically through the use of social networking analysis, which is effectively served by internet or ...
Michael Conrad Meyer   +2 more
doaj   +1 more source

Forensic Driver Identification Considering an Unknown Suspect

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2021
One major focus in forensics is the identification of individuals based on different kinds of evidence found at a crime scene and in the digital domain.
Dološ Klara   +3 more
doaj   +1 more source

Rothbard on the Economics of Slavery

open access: yesQuarterly Journal of Austrian Economics, 2020
Murray Rothbard wrote an unpublished note in the early 1960s on the economics of antebellum slavery. Essentially, it was a criticism of the methodology of the New Economic History, or cliometrics, of which Conrad and Meyer (1958a) was the breakthrough ...
Mark Thornton
doaj   +1 more source

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