Results 51 to 60 of about 1,932,719 (348)
Gene Therapy – Potential, Pros, Cons and Ethics [PDF]
, 2002 Genetic technology poses risks along with its rewards, just as any technology has in the past. To stop its development and forfeit the benefits gene therapy could offer would be a far greater mistake than forging ahead could ever be.
Rao Nanjunda, Mr Ananth
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Explaining the pros and cons of different sources of Faculty Evaluation from the viewpoints of Medical University Academics [PDF]
Strides in Development of Medical Education, 2012 Background & Objectives: Nowadays improvement of teaching quality is one of the basics for a credible higher education system and without doubt evaluation and monitoring of teaching quality are important for reaching this goal However different studies ...
Ali Asghar Arabi Mianroodi +2 more
doaj
Notifications workflows using the CERN IT central messaging infrastructure [PDF]
EPJ Web of Conferences, 2019 In the CERN IT agile infrastructure (AI), Puppet, the CERN IT central messaging infrastructure (MI) and the Roger application are the key constituents handling the configuration of the machines of the computer centre.
Toteva Zhechka, Lukic Darko, Cons Lionel
doaj +1 more source
Caveat Blogger: Blogging and the Flight from Scholarship [PDF]
, 2006 These comments were delivered to the “Symposium on Bloggership” held at Harvard Law School on April 28, 2006.
Barnett, Randy E
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Revista X, 2015 O Ensino de Jovens e Adultos (EJA), mesmo que de extrema relevância e importância no contexto sócio histórico brasileiro, ainda se apresenta como um grande desafio para os educadores nas questões de adaptação dos alunos em sala de aula, de currículo e de
Thais Rodrigues Cons
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Biotechnology Process Patents: Is Special Legislation Needed? [PDF]
, 1994 The authors review administrative and court decisions prompting proposed changes to the patent law. After reviewing pros and cons, they argue that, on balance, pending bills can easily cause more problems than they ...
Linkkila, Timothy P., Tracy, Timothy E.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source