Results 71 to 80 of about 1,932,719 (348)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Paperless assessment via VLE: the pros and the cons [PDF]

open access: yes, 2006
The aim of this short paper is to share our experience of paperless assessment using the submission facility provided in the Blackboard Virtual Learning Environment (VLE). An important part of a tutor’s work is monitoring and assessing students’ work on
Heinze, A, Whatley, J
core  

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

The pros and cons of interactive marketing to consumers and the manufacturer. Плюсы и минусы интерaктивного мaркетингa для потребителей и производителей

open access: yesХабаршысы. Экономика сериясы, 2016
In the article considered the main pros and cons of interactive marketing to consumers and producers in terms of technical and scientific progression in the spheres of social and economic communication. Many foreign and domestic scientists are considered
S. T. Kargabaeva, T. Muratkaliuly
doaj  

Farmaci innovativi e sostenibilità

open access: yesGlobal & Regional Health Technology Assessment, 2016
The recent availability of innovative, costly cancer drugs has prompted the search for a sustainable health economics model that would allow universal access to treatment coupled with long-term viability of the national health system.
Paolo Bonaretti
doaj   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang   +7 more
wiley   +1 more source

Con sin negaci?n, sin con negaci?n y con con sin

open access: yes, 2023
Este trabajo analiza la relaci?n que se establece entre la preposici?n con y la preposici?n sin, y argumenta que dicha relaci?n est? basada en la sem?ntica conceptual y no en una relaci?n gramatical. Propongo que los dos grupos de lecturas de la preposici?n con, sim?tricas y no sim?tricas, se diferencian por la estructura sint?ctica interna de la ...
openaire   +1 more source

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