Results 31 to 40 of about 1,765 (210)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Journal of Biochemical and Clinical Genetics, 2021 Background: There is a high rate of consanguinity and related genetic diseases in the general population of Saudi Arabia. Studies have been conducted to address the level of awareness about consanguineous marriages (CM); however, targeted young female ...
Hadil Alahdal +7 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Consanguinity and Dysmorphology in Arabs [PDF]
Human Heredity, 2014 Incidence rates of congenital disorders among the 350 million inhabitants of Arab countries could be influenced via the people's demographic and cultural characteristics. Arabs usually marry at a young age and have large families. They share certain core cultural values and beliefs, with the family accepted as the central structure of society ...
Lihadh, Al-Gazali, Hanan, Hamamy
openaire +2 more sources
The changing pattern and determinants of declining consanguinity in Jordan during 1990–2012
Annals of Human Biology, 2018 Background: Consanguinity is a deep rooted cultural trait in Jordan. Aim: To examine the patterns and determinants of declining rates of consanguineous marriage in Jordan during 1990–2012 in the context of the changing pattern of socio-economic and ...
M. Mazharul Islam
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Molecular Genetics & Genomic Medicine, 2021 Background Primary microcephaly (PM) is defined as a significant reduction in occipitofrontal circumference (OFC) of prenatal onset. Clinical and genetic heterogeneity of PM represents a diagnostic challenge.
Sarah Duerinckx +37 more
doaj +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Consanguinity and its Effects : The Love That Dare Not Speak Its Surname! [PDF]
Perspectives In Medical Research, 2017 Introduction: Consanguineous marriage means marrying biologically related or blood relatives. Consanguinity is a deeply rooted trend in the South Indian States.
N Sreeja1 , Rupshikha Dutta2
doaj
Egyptian Journal of Medical Human Genetics, 2019 Background Despite the numerous studies confirming the involvement of consanguinity in health problems, some populations around the world continue to practice this marital behavior.
Said Bachir, Ammaria Aouar
doaj +1 more source