Results 61 to 70 of about 6,343 (253)
Advanced Science, EarlyView.Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza +9 more
wiley +1 more source
Epidemics of poliomyelitis in the Maltese island of Gozo : genetic susceptibility [PDF]
, 2014 There were fewer epidemics of polio in Gozo than in the much bigger island of Malta, but over many years the proportion of cases was similar. Within Gozo, the attack rate was greater in some villages and this was caused by some extended, related families
Wyatt, H. V.
core
Histoires d’identité (génétique)
Bulletins et Mémoires de la Société d’Anthropologie de Paris, 2009 This note takes a historical perspective on the concept of genetic identity states between four alleles of two individuals. Several definitions of these states were proposed between 1940 and 1970, and states were diversely merged according to the authors.
Anne-Louise Leutenegger, Pierre Darlu
doaj +1 more source
Annals of Human Biology, 2023 Background Runs of homozygosity (ROHs) analysis of controls provide a convenient resource to minimize the association of false positive results of disease-associated ROHs and genetic variants for simple and complex disorders in individuals from the same ...
Tahira Yasmin +4 more
doaj +1 more source
Advanced Science, EarlyView.When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Frontiers in Pediatrics, 2020 Background: The prevalence of celiac disease (CD) has dramatically increased with wide variability in clinical presentations between different geographical areas.
Baruch Yerushalmi +9 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan +12 more
wiley +1 more source
Frontiers in Genetics, 2019 Recent studies of the genetic foundations of cognitive ability rely on large samples (in extreme, hundreds of thousands) of individuals from relatively outbred populations of mostly European ancestry.
Sergey A. Kornilov +9 more
doaj +1 more source
Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction
Advanced Science, EarlyView.During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao +8 more
wiley +1 more source
The Impact of Consanguinity Worldwide
Public Health Genomics, 1998 Consanguineous marriages have been practiced for hundreds of years in many parts of the world. The rate of congenital malformations among the offspring is 2.5 times higher than that among the offspring of unrelated parents, mainly due to the expression of autosomal-recessive disorders, and hospitalization for these reasons causes a major financial ...
L, Jaber, G J, Halpern, M, Shohat
openaire +2 more sources