Results 61 to 70 of about 54,157 (345)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Consanguinity and major genetic disorders in Saudi children : A community-based cross-sectional study

Annals of Saudi Medicine, 2008
Background and Objectives: There is a high rate of consanguinity in Saudi Arabia; however, information on its relationship with genetic disorders is limited. The objective of this cross-sectional study was to explore the role of consanguinity in genetic
El Mouzan Mohammad, Al Salloum Abdullah, Al Herbish Abdullah, Qurachi Mansour, Al Omar Ahmad   +4 more
doaj  

Epidemics of poliomyelitis in the Maltese island of Gozo : genetic susceptibility [PDF]

, 2014
There were fewer epidemics of polio in Gozo than in the much bigger island of Malta, but over many years the proportion of cases was similar. Within Gozo, the attack rate was greater in some villages and this was caused by some extended, related families
Wyatt, H.V.
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Post-surgical dentofacial deformities and dental treatment needs in cleft-lip-palate children: A clinical study

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Background: Cleft lip and palate is a common congenital defect. It is one of the most common facial deformities occurring in major racial and ethnic groups.
V Krishna Priya, J Sharada Reddy, Y Ramakrishna, C Pujita Reddy   +3 more
doaj   +1 more source

Experimentation with Animals: A Key Aspect of the 3Rs. The Genetic Quality [PDF]

, 2019
The genetic quality of laboratory animals is essential for reproducibility of scientific research. Working with animals of certifiedgenetic quality is still a pending issue in Argentina due to the lack of routine genetic controls, of information on the ...
Castillo, Nadia Sabiela, Giovambattista, Guillermo, Lizarraga, Maria Alfonsina, Posik, Diego Manuel, Zappa, María Eugenia   +4 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Spatial and temporal variability of consanguinity in the French Cerdagne

Pirineos: Revista de Ecología de Montaña, 1993
[es] En este trabajo se ha estudiado la consanguinidad de la comarca pirenaica de la Cerdaña francesa desde 1836 a 1990. El cálculo de las frecuencias de matrimonios consanguíneos y del coeficiente a muestra que la consanguinidad de esta población es ...
Marta Vigo
doaj   +1 more source

Regulating Sperm Donation: Why Requiring Exposed Donation Is Not the Answer [PDF]

, 2009
[...] the risk of incest and consanguinity11 are prevalent with anonymous donation12 since there is no monitoring of the number of live births per donor.
Pi, Vanessa L.
core   +1 more source