Results 81 to 90 of about 6,343 (253)
Empirical estimates of the global prevalence of consanguineous marriage in contemporary societies
, 1998 Although marriages between close biological kin are preferential in many parts of the world, there still is a remarkable lack of knowledge of this central feature of human kinship structure, in particular how consanguinity might influence reproductive ...
Bittles, A.H.
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Studies on Maltese Consanguinity [PDF]
, 2003 The possible genetic consequences of consanguinity have been known from ancient times, though different societies have held varying views. Some have encouraged consanguinity as desirable and the classic examples are the sister brother marriages of the ...
Vassallo, Luis A.
core
Is Consanguinity an Impediment to Child Development?
, 2020 Marriages between blood relatives—also known as consanguineous unions—are widespread in North Africa, Central and West Asia, and South Asia. Researchers have suggested that consanguinity has adverse effects on child development, but assessing its impact ...
Mete, Cem +3 more
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Frontiers in Reproductive HealthBackgroundConsanguineous marriages remain prevalent in many regions of the world, particularly within the Middle East, where reported prevalence exceeds 50% in countries such as Saudi Arabia, Oman, and the United Arab Emirates.
Rasha Bayoumi +4 more
doaj +1 more source
Advanced Science, EarlyView.Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao +25 more
wiley +1 more source
Consanguinity and chromosomal abnormality
, 2005 BACKGROUND: Consanguinity is defined as the marriage between close relatives. The deleterious effects associated with consanguinity may be caused by the expression of rare recessive genes inherited from common ancestors.
S. Amudha, N. Aruna, S. Rajangam
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A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates
Advanced Science, EarlyView.Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao +7 more
wiley +1 more source
Advanced Science, EarlyView.A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng +5 more
wiley +1 more source
Time to Get Real: Investigating Potential Beneficial Genetic Aspects of Consanguinity
, 2011 The extensive and well-documented application of close genetic crosses in animal and plant breeding has amply demonstrated that, from a biological perspective, inbreeding is not necessarily detrimental, although a substantial price may have to be paid ...
Bittles, A.H.
core +1 more source
Impact of parental consanguinity on clinical features in schizophrenia
, 2017 Objective: The purpose of this study was to evaluate the impact of parental consanguinity on the clinical features in schizophrenia. Methods: The sample of the study was based on DSM-IV schizophrenia patients admitted to Ataturk State Hospital of Sinop ...
Ulas, Halis +5 more
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