Results 91 to 100 of about 13,996 (241)

ENDOGAMY, CONSANGUINITY AND THE HEALTH IMPLICATIONS OF CHANGING MARITAL CHOICES IN THE UK PAKISTANI COMMUNITY

Journal of Biosocial Science, 2016
Summary The biraderi (brotherhood) is a long-established, widely prevalent dimension of social stratification in Pakistani communities worldwide. Alongside consanguinity, it offers a route for cementing social solidarities and so has strong socio ...
N. Small, A. Bittles, E. Petherick, John Wright   +3 more
semanticscholar   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Enhanced growth of short stature in Ellis-van Creveld syndrome: A case report of a Saudi child

Saudi Journal for Health Sciences
This case report presents the diagnosis and management of Ellis-van Creveld syndrome (EVC) in a 20-year-old Saudi boy, highlighting the condition’s genetic basis and prevalence in consanguineous communities.
Essam Al Ageeli
doaj   +1 more source

The Kuwait National Primary Immunodeficiency Registry 2004–2018

Frontiers in Immunology, 2019
Objective: To present the report from the Kuwait National Primary Immunodeficiency Registry between 2004 and 2018.Methods: The patients were followed prospectively between January 2004 and December 2018 and their collected data included sociodemographic,
Waleed Al-Herz, Waleed Al-Herz, Mona Al-Ahmad, Mona Al-Ahmad, Ahmad Al-Khabaz, Ahmed Husain, Ali Sadek, Yasmeen Othman   +7 more
doaj   +1 more source

Consanguinity Among Parents of Iranian Deaf Children

Iranian Red Crescent Medical Journal, 2016
Background It seems that there is a relationship between consanguinity and profound hearing loss but there is little data about the association of consanguinity and hearing loss in Iran.
Mohammad Ajallouyan, S. Radfar, S. Nouhi, Seid Abbas Tavallaie, S. Amirsalari, Jaleh Yousefi, Mahdieh Hasanali Fard   +6 more
semanticscholar   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Classification Regression Methods in Identification of the Interactive Effects of the Risk Factors of Cerebral Palsy in Children

مجله اپیدمیولوژی ایران, 2014
Background & Objectives : The identification of risk factors and their interactions is important in medical studies. The aim of this study was to identify the interaction of risk factors of cerebral palsy in 1-6 years-old children with classification ...
S Zare Delavar , E Bakhshi, F Soleimani, A Biglarian   +3 more
doaj  

Incidence and long-term outcomes of dextro-transposition of the great arteries (d-TGA) in the Kingdom of Bahrain

Frontiers in Cardiovascular Medicine
BackgroundDextro-Transposition of the Great Arteries (d-TGA) is a rare cyanotic congenital heart defect requiring surgical correction for survival. The arterial switch operation (ASO) is the preferred approach, offering favorable long-term outcomes ...
Ahmed J. AlAraibi, Fatema Naser Shakeeb, Zahra Naser Shakeeb, Salim Fredericks, Aditya Bhat, N. N. Kalis   +5 more
doaj   +1 more source

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Prevalence, Structure, and Perception of the Local Population Regarding Consanguineous Marriages in the Rural Areas of Southern India: A Community based Mixed Methods Study

Indian Journal of Public Health
Background: Southern India has one of the highest prevalence of consanguineous marriages in Asia. Limited research has been conducted to understand the reasons behind this in the rural areas of South India, despite the potential risks associated with ...
Dakshita Narayanam, Mishu Mangla, Gomathi Ramaswamy, Remya Mary John   +3 more
doaj   +1 more source