Results 101 to 110 of about 50,599 (306)

Why and how do we perform physical examination(s) in clinical trials? A use case of drug intervention trials in type 2 diabetes mellitus

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this study was to determine the purpose and use of physical examination (PE) in phase 3 and 4 drug interventional clinical trials within type 2 diabetes mellitus. Methods A total of 226 clinical trial protocols identified from the ClinicalTrials.gov database were systematically reviewed by five researchers.
Julia Kopanz, Amy Rogers, Lina Pérez‐Breva, Emily Hall, Prashasthi Devaiah, Isla S. Mackenzie, Bart Lagerwaard, Diederick E. Grobbee, Mira G. P. Zuidgeest, on behalf of the Trials@Home consortium   +9 more
wiley   +1 more source

Fostamatinib and the risk of acute aortic dissection in immune thrombocytopenia

British Journal of Clinical Pharmacology, EarlyView.
Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by platelet destruction. While most patients respond to first‐ or second‐line therapies, a small subset is multirefractory. Fostamatinib, an oral spleen tyrosine kinase (SYK) inhibitor, is a therapeutic option in these cases.
Paul Dalmas, Alexis Theron, Rita Badaoui, Stéphane Zaffran, Rayid Mchinda, Joelle Micallef, Nicolas Schleinitz, Mikael Ebbo   +7 more
wiley   +1 more source

Conscious Sedation with Remifentanil During Painful Medical Procedures [PDF]

, 2000
Ronald S. Litman
openalex   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Understanding Conscious Sedation in the Operating Room

, 1998
Mary Golinski
openalex   +2 more sources

Propofol sedation does not improve measures of colonoscopy quality but increase cost – findings from a large population-based cohort studyResearch in context

EClinicalMedicine
Summary: Background: Propofol is often used for sedation during colonoscopy. We assessed the impact of propofol sedation on colonoscopy related quality metrics and cost in a population-based cohort study.
Sheikh Rahman, Lauren E. Cipriano, Cassandra McDonald, Sarah Cocco, Ziad Hindi, Debarati Chakraborty, Karissa French, Omar Siddiqi, Mayur Brahmania, Aze Wilson, Brian Yan, Leonardo Guizzetti, Vipul Jairath, Michael Sey   +13 more
doaj   +1 more source

Target-Controlled Infusion of Propofol for Conscious Sedation Using BIS Monitor [PDF]

, 2000
Dong Hee Kim, Byung Kyu Sohn
openalex   +1 more source

Evaluation of recovery after intravenous sedation [PDF]

, 2017
The Intravenous Sedation (IVS) Guideline Working Group of the Japanese Dental Society of Anesthesiology (JDSA) formulated guidelines for intravenous conscious sedation in dentistry.
Fujisawa, Toshiaki, Shibuya, Makiko
core  

Signaling Sustainability: The Impact of Sustainable Finance on Dividend Policy Among Firms Listed on the London Stock Exchange

Business Strategy and the Environment, EarlyView.
ABSTRACT The UK regulatory framework mandates that firms report their social and environmental implications, ensuring that sustainability factors are incorporated into policy formulation, including dividend policies. For this reason, the study examined how sustainable finance of the firms listed on the London Stock Exchange impacts dividend policy. The
Richard Arhinful, Hayford Asare Obeng, Leviticus Mensah, Comfort Constance Mensah   +3 more
wiley   +1 more source

Echocardiographic evaluation of velocity ratio, velocity time integral ratio, and pulmonary valve area in dogs with pulmonary valve stenosis. [PDF]

, 2018
BackgroundVelocity ratio, velocity time integral (VTI) ratio, and pulmonary valve area indexed to body surface area (iPVA) are methods of assessment of pulmonary valve stenosis (PS) severity that are less dependent on blood flow. Studies evaluating these
Bélanger, Catherine, Gunther-Harrington, Catherine T, Nishimura, Satoko, Oldach, Maureen S, Stern, Joshua A, Visser, Lance C   +5 more
core   +1 more source