Results 71 to 80 of about 340,414 (353)

Research advances in the clinical application of esketamine

Ibrain, 2022
Esketamine is dextrorotatory ketamine, which is an enantiomer of ketamine. Compared with ketamine, it has the advantages of a fast metabolism, fewer side effects, and strong pharmacological effects, so it is more suitable for clinical use. Esketamine has
Xiao‐Xi Zhang, Nai‐Xin Zhang, De‐Xing Liu, Jun Ding, Yi‐Nan Zhang, Zhao‐Qiong Zhu   +5 more
doaj   +1 more source

General Anesthesia Versus Conscious Sedation for Intracranial Mechanical Thrombectomy: A Systematic Review and Meta‐analysis of Randomized Clinical Trials

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019
Background Endovascular therapy is the standard of care for severe acute ischemic stroke caused by large‐vessel occlusion in the anterior circulation, but there is uncertainty regarding the optimal anesthetic approach during this therapy.
Yu Zhang, L. Jia, Fang Fang, Lu Ma, Bo-wen Cai, A. Faramand   +5 more
semanticscholar   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Prospective associations of text‐message‐based sentiment with symptoms of depression, generalized anxiety, and social anxiety

Depression and Anxiety, Volume 39, Issue 12, Page 794-804, December 2022., 2022
Abstract Objective Language patterns may elucidate mechanisms of mental health conditions. To inform underlying theory and risk models, we evaluated prospective associations between in vivo text messaging language and differential symptoms of depression, generalized anxiety, and social anxiety. Methods Over 16 weeks, we collected outgoing text messages
Caitlin A. Stamatis, Jonah Meyerhoff, Tingting Liu, Garrick Sherman, Harry Wang, Tony Liu, Brenda Curtis, Lyle H. Ungar, David C. Mohr   +8 more
wiley   +1 more source

A randomised controlled trial comparing high‐flow nasal oxygen with standard management for conscious sedation during bronchoscopy

Anaesthesia, 2018
Traditional conscious sedation for endobronchial ultrasound procedures places patients at risk of desaturation, and high‐flow nasal oxygen may reduce the risk.
N. Douglas, I. Ng, F. Nazeem, K. Lee, P. Mezzavia, R. Krieser, Daniel P Steinfort, L. Irving, R. Segal   +8 more
semanticscholar   +1 more source

The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies

Advanced Science, EarlyView.
This work explores the process of morning awakening of the human brain using polysomnography paired with simultaneous stereo‐electroencephalography, a method that provides high spatial and temporal resolution for examining brain activity. Awakening is characterized by an increase in high‐frequency spectral power and connectivity.
Tamir Avigdor, Guoping Ren, Chifaou Abdallah, François Dubeau, Christophe Grova, Birgit Frauscher   +5 more
wiley   +1 more source

Propofol versus meperidine and midazolam as a conscious sedation in percutaneous vertebroplasty: Prospective randomized trial

The Indian Anaesthetists' Forum, 2018
Background: Percutaneous vertebroplasty is a minimally invasive procedure, usually performed under local anesthesia with either general anesthesia or conscious sedation.
Asmaa Fawzy Amer, Eman Ramadan Salama, Hytham Ibrahim Elatrozy   +2 more
doaj   +1 more source

General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke)

Stroke, 2017
Background and Purpose— Retrospective studies have found that patients receiving general anesthesia for endovascular treatment in acute ischemic stroke have worse neurological outcome compared with patients receiving conscious sedation.
P. Löwhagen Hendén, A. Rentzos, J. Karlsson, L. Rosengren, Birgitta Leiram, H. Sundeman, Dennis Dunker, K. Schnabel, G. Wikholm, M. Hellström, S. Ricksten   +10 more
semanticscholar   +1 more source

Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism

Advanced Science, EarlyView.
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini, Sabrina Mechaussier, Carolina Campos Pina, Monica Morais, Olivier Postal, Philippe Jean, Typhaine Dupont, Amrit Singh‐Estivalet, Shéhanie Udugampolage, Cyril Scandola, Elisabeth Verpy, Baptiste Libé‐Philippot, Talya C. Inbar, Joanna Schwenkgrub, Carla Maria Barbosa Spinola, Raphaël Etournay, Aziz El‐Amraoui, Brice Bathellier, Adeline Mallet, Sedigheh Delmaghani, Fabrice Giraudet, Christine Petit, Boris Gourévitch, Paul Avan, Nicolas Michalski   +24 more
wiley   +1 more source

Complications of Conscious Sedation

Gastrointestinal Endoscopy Clinics of North America, 1996
Complications are a part of the practice of medicine. This is amply true for gastrointestinal endoscopy. The medications currently used in the practice of gastrointestinal endoscopy are essential to our ability to perform the wide array of diagnostic and therapeutic procedures that have become the hallmark of modern day gastroenterology.
openaire   +3 more sources