Results 61 to 70 of about 1,839,651 (350)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Losing the Self in Near-Death Experiences: The Experience of Ego-Dissolution
Brain Sciences, 2021 Many people who have had a near-death experience (NDE) describe, as part of it, a disturbed sense of having a “distinct self”. However, no empirical studies have been conducted to explore the frequency or intensity of these effects.
Charlotte Martial +6 more
doaj +1 more source
Is Consciousness Intrinsic?: A Problem for the Integrated Information Theory [PDF]
, 2019 The Integrated Information Theory of consciousness (IIT) claims that consciousness is identical to maximal integrated information, or maximal Φ. One objection to IIT is based on what may be called the intrinsicality problem: consciousness is an intrinsic
Mørch, Hedda Hassel
core
Oppy on the Argument from Consciousness: A Rejoinder [PDF]
, 2011 Graham Oppy had criticized my argument for God from consciousness (AC) in my recent book ’Consciousness and the Existence of God’ (N.Y.: Routledge, 2008). In this article I offer a rejoinder to Oppy.
Moreland, J. P.
core +1 more source
Folk psychological attributions of consciousness to large language models
Neuroscience of ConsciousnessTechnological advances raise new puzzles and challenges for cognitive science and the study of how humans think about and interact with artificial intelligence (AI).
Clara Colombatto, Stephen M. Fleming
semanticscholar +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Consciousness and Intentionality in Anton Marty’s Lecture on Descriptive Psychology [PDF]
, 2017 : In this study, I propose to examine Marty’s reconstruction of the general framework in which Brentano develops his theory of consciousness.
Fisette, Denis
core +1 more source
The Search for Invertebrate Consciousness [PDF]
, 2020 There is no agreement on whether any invertebrates are conscious and no agreement on a methodology that could settle the issue. How can the debate move forward?
Birch, Jonathan
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Brain Sciences, 2023 Mild traumatic brain injury (mTBI), or concussion, can lead to persistent cognitive and functional symptoms that impede quality of life to a varying extent. This condition is referred to as post-concussive syndrome (PCS).
Géraldine Martens +4 more
doaj +1 more source