Results 71 to 80 of about 308,973 (295)
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang +7 more
wiley +1 more source
Scientific Reports, 2019 The neuronal connectivity patterns that differentiate consciousness from unconsciousness remain unclear. Previous studies have demonstrated that effective connectivity, as assessed by transcranial magnetic stimulation combined with electroencephalography
Minji Lee +7 more
doaj +1 more source
Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
Communications Biology, 2021 López-González et al study the fMRI brain dynamics and their underlying mechanism from patients that suffered brain injuries leading to a disorder of consciousness as well as from healthy subjects undergoing propofol-induced sedation.
Ane López-González +11 more
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Visual consciousness and bodily self-consciousness [PDF]
Current Opinion in Neurology, 2015 In recent years, consciousness has become a central topic in cognitive neuroscience. This review focuses on the relation between bodily self-consciousness - the feeling of being a subject in a body - and visual consciousness - the subjective experience associated with the perception of visual signals.Findings from clinical and experimental work have ...
Faivre, Nathan +2 more
openaire +4 more sources
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Perception of diagnosis by family caregivers in severe brain injury patients in China
BMC Palliative CareObjectives Surrogate decision-making by family caregivers for patients with severe brain injury is influenced by the availability and understanding of relevant information and expectations for future rehabilitation. We aimed to compare the consistency of
Yifan Yan +8 more
doaj +1 more source
Data-based intervention approach for Complexity-Causality measure [PDF]
PeerJ Computer Science, 2019 Causality testing methods are being widely used in various disciplines of science. Model-free methods for causality estimation are very useful, as the underlying model generating the data is often unknown.
Aditi Kathpalia, Nithin Nagaraj
doaj +2 more sources
Frontiers in Neurology, 2018 Background: Disorders of consciousness are challenging to diagnose, with inconsistent behavioral responses, motor and cognitive disabilities, leading to approximately 40% misdiagnoses.
Francesco Riganello +13 more
doaj +1 more source