Results 51 to 60 of about 3,010 (299)

New religiosity and its socio-cultural perspectives in Ukraine

open access: yesУкраїнське Pелігієзнавство, 2009
In modern humanities, the notion of "new religiosity", as well as language constructs related to it - "unconventional religiosity", "new religions", "new religious consciousness", "new religious movements", etc., has become widespread.
Hanna M. Kulagina-Stadnichenko
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Discernimento del Superiore religioso: la postulazione

open access: yesThe Person and the Challenges, 2015
The main purpose of the present submission relates to the matter of the postulation regulated by the legal disposition expressed in canons 180 e 181 CIC/83.
Przemysław Michowicz
doaj   +1 more source

Gerotranscendence, religiosity, and life satisfaction: a study with clergy and consecrated religious individuals

open access: yes, 2021
Gerotranscendence explains the psychosocial changes in later life and how one acquires a more transcendent life view. This study seeks to increase the evidence on the association between gerotranscendence, life satisfaction, and religiosity. Specifically,
Araújo, Lia   +2 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The Status of the Consecrated Person in the Teaching of John Paul II

open access: yesKościół i Prawo, 2014
Autor analizuje ostatnie zmiany dotyczące postrzegania statusu prawnego osoby konsekrowanej w ludzie Bożym. Pojęcia wprowadzone na Soborze Watykańskim II, jak i pojawienie się nowych form życia konsekrowanego w Kodeksie Prawa Kanonicznego z 1983 r ...
Maria Van Scott
doaj  

Reflections on the situation of nuns in the Roman Catholic Church with illustrative examples from Spanish-language literature

open access: yesActa Universitatis Lodziensis: Folia Sociologica, 2020
In 2018 and 2019, the Vatican newspaper “L’Osservatore Romano” published two ground-breaking articles describing the psychological, physical and sexual abuse of nuns by clergymen of the Roman Catholic Church.
Olga Grzyś
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Laypeople in Discernment and Governance of the Catholic Church: Current Situation and Prospects

open access: yesVerbum Vitae
This article explores lay participation in discernment and governance across various aspects of the Church’s life, considering the prospects for development and the theological limits of the proposed solutions.
Przemysław Sawa
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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