Results 61 to 70 of about 58,725,068 (254)

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Liquid–Liquid Equilibrium Data for Refined Olive Pomace Oil + Oleic Acid + Ethanol + Water Systems: Application to Solvent Deacidification

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT This study presents the first experimental liquid–liquid equilibrium (LLE) data for quaternary systems composed of refined olive pomace oil, oleic acid, ethanol, and water at 303.15 K. These data are essential for the design and optimization of solvent‐based deacidification processes, particularly for oils with high free fatty acid (FFA ...
Jacqueline Mansano Ortega, Andresa Feihrmann, Guilherme Duenhas Machado, Lucio Cardozo‐Filho, Francisco Adrian Sánchez, Vladimir Ferreira Cabral   +5 more
wiley   +1 more source

Development of the nasal capsule in Emydura subglobosa (Testudines: Pleurodira) with a comparison to other turtles

The Anatomical Record, EarlyView.
Abstract Extant turtles occupy freshwater, marine, and terrestrial habitats, and their nasal region provides important evidence for the evolution of respiration‐ and sensory‐related cranial morphology. However, developmental data on the turtle nasal capsule remain limited, particularly in Pleurodira.
Kai Ito, Paweł Kaczmarek, Taro Nojiri, María Victoria Fernandez Blanco, Ryo Kodera, Ingmar Werneburg   +5 more
wiley   +1 more source

Fortalecimiento del consejo nacional de ciencia y tecnología.

, 2013
Breve reseña história del Consejo Nacional de Ciencia Tecnología y fortalecimientos que ha tenido desde sus inicio en 1992 hasta la ...
Consejo Nacional de Ciencia y Tecnología (CONACYT)
core  

Impaired Motor Competence in Children and Adolescents With Autism Spectrum Disorder: Evidence From a Systematic Review and Meta‐Analysis

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is frequently associated with motor difficulties that may affect daily functioning, participation in physical activity, and developmental outcomes. Although motor impairments have been widely reported in this population, comparative evidence against typically developing (TD) peers remains fragmented across ...
Nerea Blanco‐Martínez, Daniel González‐Devesa, Silvia Varela, Rocío Carballo‐Afonso, Carlos Ayán‐Pérez   +4 more
wiley   +1 more source

Synergetic Combination of Carbon Xerogels, Graphene Oxide and nano‐ZnO for Aqueous and Organic Supercapacitors

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
This work proposes the synthesis of carbon‐based nanostructured materials obtained using ZnO as both nanos‐ template and catalysts simultaneously. During the synthesis, GO was used as a stabiliser, preventing the collapse of the 3D structure and improving its properties in terms of capacitance and surface area.
Rusbel Coneo‐Rodríguez, Alvaro Yamil Tesio, Fernando Pablo Cometto, Gustavo Marcelo Morales, Gabriel Ángel Planes, Alvaro Caballero   +5 more
wiley   +1 more source

Unmasking Glycoforms: Lectin‐Based Profiling and Functional Implications of Targeted Glycosylation Knockouts in Chinese Hamster Ovary Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Monoclonal antibody (mAb) glycosylation is a critical quality attribute that is difficult to rationally engineer and rapidly assess during cell line development. Here, we investigate whether cell‐surface glycosylation can serve as a surrogate readout of mAb product glycosylation following targeted glycogene engineering in CHO cells.
Cristina Abascal Ruiz, Sheryl Li Yan Lim, Jacobus Brink, Sara Carillo, Eoin Casey, Jonathan Bones, Ioscani Jiménez del Val   +6 more
wiley   +1 more source

Informe del Presidente del Consejo de Estado al Congreso Ordinario de 1903 (Folleto).

, 1903
CON verdadero agrado cumplo mi deber de informaros acerca de las labores del Consejo de Estado, pues en todas las resoluciones de esta elevada Corporación, los Señores Consejeros se han mantenido á la altura que sus precedentes y delicado cargo les ...
Consejo de Estado
core  

Carrion ecology: concepts, interdisciplinary synthesis, and perspectives

Biological Reviews, EarlyView.
ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón, José A. Sánchez‐Zapata, Travis L. DeVault, Wayne M. Getz, Zebensui Morales‐Reyes, Daniel Redondo‐Gómez, Lara Naves‐Alegre, Solange A. Batista‐Nunes, Esther Sebastián‐González, Juan M. Pérez‐García, Kelly A. Waters, Thijs van Overveld, Craig Smith, Nuria Selva, Thomas A. Schlacher, Graeme Ruxton, Jesús Rodríguez, Martina‐M. Quaggiotto, Paula L. Perrig, Norman Owen‐Smith, Thomas M. Newsome, Isabel Navas, Yoshihiro Nakashima, Ana Mateos, Carlos Martínez‐Carrasco, Daniel Martín‐Vega, Berta Martín‐López, Antoni Margalida, Sergio A. Lambertucci, Adam Kane, Kevin Healy, Akane Hashizume, Antonio J. García‐Fernández, José A. Donázar, M. Eric Benbow, James C. Beasley, Philip S. Barton, Kathleen A. Alexander, Eneko Arrondo   +38 more
wiley   +1 more source

Concepto Autor Consejo de Estado

, 2011
Sociedad De Economía Mixta, Entidad Pública, Recursos Públicos, Funciones De La Cámara De ...
Consejo de Estado
core   +1 more source