Results 91 to 100 of about 4,259,195 (377)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

What steps are necessary to create written or web-based selected-response assessments? [PDF]

open access: yesJournal of Educational Evaluation for Health Professions, 2014
Before we work out what constitutes an assessment’s value for a given cost in medical education, we must first outline the steps necessary to create an assessment, and then assign a cost to each step.
Matt Morgan   +3 more
doaj   +1 more source

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

open access: yesNeurology, 2015
Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies (AQP4-IgG).
D. Wingerchuk   +18 more
semanticscholar   +1 more source

A New Hearing: Living Options in Homiletic Method [PDF]

open access: yes, 1991
Reviewed Book: Eslinger, Richard L. A New Hearing: Living Options in Homiletic Method.
Nevile, Donald
core   +2 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Consensus science, or consensus politics? [PDF]

open access: yesNature, 2001
To some, the Intergovernmental Panel on Climate Change represents the pinnacle of scientific collaboration. To others, it is a victory for politics over science. Mark Schrope talks to the experts debating our planet's future.
openaire   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

The Definition of Paramedicine: An International Delphi Study

open access: yesJournal of Multidisciplinary Healthcare, 2021
Brett Williams, Bronwyn Beovich, Alexander Olaussen Department of Paramedicine, Monash University, Melbourne, Victoria, AustraliaCorrespondence: Brett WilliamsDepartment of Paramedicine, Monash University, Peninsula Campus, PO Box 527, McMahons Road ...
Williams B, Beovich B, Olaussen A
doaj  

Neighbourhood Consensus Networks [PDF]

open access: yes, 2018
We address the problem of finding reliable dense correspondences between a pair of images. This is a challenging task due to strong appearance differences between the corresponding scene elements and ambiguities generated by repetitive patterns.
Arandjelović, Relja   +5 more
core   +1 more source

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