Results 81 to 90 of about 4,028,254 (313)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
An introduction to the Old Testament: the canon and Christian imagination [PDF]
, 2006 Title: An introduction to the Old Testament: the canon and Christian imagination. Author: Brueggemann, Walter Introduction to the Old Testament xiv, 417 p.
Uitti, Roger W.
core +1 more source
Distributed Computing, 2014 The unbeatability of a consensus protocol, introduced by Halpern, Moses and Waarts in 2001, is a stronger notion of optimality than the accepted notion of early stopping protocols. Using a novel knowledge-based analysis, this paper derives the first practical unbeatable consensus protocols in the literature, for the standard synchronous message-passing
Armando Castañeda +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
, 2003 Author: Thurston, Bonnie Bowman Title: Preaching Mark. Publisher: Minneapolis: Fortress, 2002.
Eckert, Rebekah
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Expert Consensus on the Clinical Utilization of Ketamine and Its Isomers in Intensive Care Units
Intensive Care ResearchAnalgesia and sedation are important treatment strategies in the intensive care unit (ICU). Due to the opioid crisis, opioid-sparing medications become the focus of clinical studies.
Zhiyong Peng +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
How to reach a compromise solution on technical and non-structural flood control measures
Soil and Water Research, 2014 Harmful impacts of floods are the result of an interaction between extreme hydrological events and environmental, social, and economic processes. Flood management should consider many diverse aspects and influences and an integrated approach to flood ...
Pavel KOVÁŘ +3 more
doaj +1 more source