Results 61 to 70 of about 249,976 (301)

Equity decentralized consensus algorithm based on incentive compatibility

Tongxin xuebao, 2022
The PoW consensus algorithm has been proved to be incentive incompatible, existing computing centralization under high reward differences and slow convergence of forks in extreme cases.Based on this, an incentive-compatiblebased consensus algorithm SSPoW
Youliang TIAN, Yansen YUAN, Hongfeng GAO, Yang YANG, Jinbo XIONG   +4 more
doaj  

CAGE - Consensus Algorithm Genetically Encouraged [PDF]

, 2022
Blockchain Technology has gone beyond just cryptocurrency. There is a growing need not only for development in blockchain technology to support the needs of Web 3.0, but also a need for research into Blockchain Technology.
Maka, K.
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Optimization of PBFT Algorithm Based on QoS-Aware Trust Service Evaluation

Sensors, 2022
In service-transaction scenarios, blockchain technology is widely used as an effective tool for establishing trust between service providers and consumers. The consensus algorithm is the core technology of blockchain.
Wei Liu, Xuhao Zhang, Wenlong Feng, Mengxing Huang, Yun Xu   +4 more
doaj   +1 more source

Proof-of-Work as a Stigmergic Consensus Algorithm [PDF]

International Joint Conference on Autonomous Agents and Multiagent Systems, 2022
In this paper, we make a theoretical analysis from a coordination perspective and conclude that the Proof-of-Work (PoW) algorithm is a stigmergic consensus algorithm where the trace left by an action in the blockchain through indirect coordination of agents stimulates subsequent actions and eventually creates a single chain of blocks.
openaire   +2 more sources

A simulated annealing algorithm for finding consensus sequences

, 2002
Motivation: A consensus sequence for a family of related sequences is, as the name suggests, a sequence that captures the features common to most members of the family.
Kroese, Dirk P., Kroese, Dirk P, Cochran, Duncan A., Bryant, Darryn, Keith, Jonathan M., Adams, Peter, Keith, Jonathan M, Cochran, Duncan A. E., Mitchelson, Keith R, Mitchelson, Keith R., Lala, Gita H.   +10 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Distributed Low-Carbon Economic Dispatch for Integrated Energy System Based on Homomorphic Encryption

Zhongguo dianli
To address the privacy leakage problem in the distributed scheduling process of the integrated energy system (IES), a fully consensus low-carbon economic dispatching method based on homomorphic encryption is proposed with consideration of the power ...
Jingcheng HU, Yunhao FAN, Tong ZHU, Zhenping CHEN   +3 more
doaj   +1 more source

Delegated Proof of Stake With Downgrade: A Secure and Efficient Blockchain Consensus Algorithm With Downgrade Mechanism

IEEE Access, 2019
Blockchain technology has a wide range of applications in the fields of finance, credit reporting and intellectual property, etc. As the core of blockchain, consensus algorithm affects the security and performance of blockchain system directly.
Fan Yang, Wei Zhou, QingQing Wu, Rui Long, Neal N. Xiong, Meiqi Zhou   +5 more
doaj   +1 more source