Results 101 to 110 of about 3,887,385 (233)

Research on consensus mechanism optimization for IoT blockchain

open access: yesDianxin kexue, 2020
The essence of the blockchain is a decentralized distributed ledger system.The Internet of things is interconnected by massive heterogeneous terminals and has natural distributed characteristics.Therefore,the combinedIoT blockchain is widely optimistic ...
Qijie SONG   +4 more
doaj  

Reaching a consensus on the mechanism of dynamin? [PDF]

open access: yesF1000Prime Reports, 2014
AMONG THE PROTEINS INVOLVED IN LIPID MEMBRANE REMODELING IN INTRACELLULAR TRAFFIC, DYNAMIN HAS BEEN THE FOCUS OF MANY STUDIES, AS IT WAS THE FIRST PROTEIN SHOWN TO BE MECHANISTICALLY INVOLVED IN MEMBRANE FISSION: the reaction by which a vesicle neck can be severed to release a free vesicle. After almost 25 years of research, a wide variety of data from
openaire   +4 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

The dynamics of consensus in group decision making: investigating the pairwise interactions between fuzzy preferences. [PDF]

open access: yes
In this paper we present an overview of the soft consensus model in group decision making and we investigate the dynamical patterns generated by the fundamental pairwise preference interactions on which the model is based.
Matteo Brunelli   +3 more
core  

Design of a crab-like bistable mechanism for nearly equal switching forces in forward and backward directions

open access: yes, 2018
A compliant bistable mechanism with a crab-like structure for nearly equal switching forces in the forward and backward directions is developed. It consists of four crab-leg-like beams and a shuttle mass.
Dung-An Wang   +2 more
core   +1 more source

Research on cross-domain trustable blockchain based decentralized DNS architecture

open access: yes网络与信息安全学报, 2020
The domain name system (DNS) is an important internet infrastructure.However,current DNS utilizes centralized hierarchical structure with severe dependence on root server,which causes defects such as the risk of single-point failure and the abuse of ...
Kai LEI   +3 more
doaj  

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