Results 81 to 90 of about 3,887,385 (233)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2022 Title from PDF caption (viewed on June 27, 2022)."This Fact Sheet was developed by the National Policy Consensus Center to supplement its independent evaluation of the pilot-phase of placebased integrated water resources planning."This archived document ...
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
LVTM: A lightweight blockchain-based V2G terminal trust management method
CSEE Journal of Power and Energy SystemsAs an important part of the smart grid (SG), Vehicle-to-Grid (V2G) has significantly advanced the development of the grid. However, the open nature of V2G system itself and the deployment of charging piles (CPs) increase the difficulty of terminal ...
Jiexiao Yu +3 more
doaj +1 more source
, 2006 ObjectivesA globally acceptable definition and classification of gastroesophageal reflux disease (GERD) is desirable for research and clinical practice.
Jones, R +14 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Hybrid Consensus Mechanism (HCM) : Achieving Efficient and Secure Consensus in Blockchain Networks
SSRN Electronic Journal, 2023 Consensus mechanisms play a critical role in blockchain networks, ensuring that all participants agree on the state of the distributed ledger. However, existing consensus mechanisms have limitations in terms of efficiency, security, and decentralization.
openaire +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Consensus Report by the Italian Academy of Osseointegration on the Importance of Peri-Implant Soft Tissues [PDF]
Background and Objectives: The influence of the quantity and quality of peri-implant soft tissue on implant health and long-term maintenance is controversial.
Eriberto Bressan +5 more
core +3 more sources