Results 61 to 70 of about 3,887,385 (233)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A Secure Big Data Storage Framework Based on Blockchain Consensus Mechanism With Flexible Finality

open access: yesIEEE Access, 2023
Data security and integrity are becoming increasingly important as the volume of data being created and stored grows. A controlled third party that provides most of the existing big data security systems makes them susceptible to several security risks ...
A. Sasikumar   +5 more
doaj   +1 more source

Oregon Recycling Steering Committee process report

open access: yes, 2020
prepared by: Oregon Consensus, National Policy Consensus Center, Portland State University.Title from PDF cover (viewed on November 4, 2020)."This report is respectfully submitted to DEQ by the Oregon Consensus Facilitation Team to conclude the Recycling

core  

Possibilities of Consensus: Toward Democratic Moral Discourse

open access: yes, 1991
The concept of consensus is often appealed to in discussions of biomedical ethics and applied ethics, and it plays an important role in many influential ethical theories.
Jennings, Bruce
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Consensus statement on unicompartmental knee replacement: A collaboration between BASK and EKS

open access: yes, 2023
Background: The aim of this study was to deliver consensus recommendations for the clinical practice of unicompartmental knee arthroplasty (UKA). Methods: Members of the British Association for Surgery of the Knee (BASK) and European Knee Society (EKS ...
BASK and EKS Consensus Group   +10 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Design and Implementation of Blockchain-based Trust Gateway for Power Internet of Things

open access: yesZhongguo dianli, 2021
In order to ensure the cyber security of bulk power system, a distributed dynamic gateway architecture based on blockchain and access authentication mechanism is proposed regarding the vulnerabilities of gateway to cyberattacks in the complex ...
Bingzhen ZHAO   +3 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Delegated Proof of Reputation Consensus Mechanism for Blockchain-Enabled Distributed Carbon Emission Trading System

open access: yesIEEE Access, 2020
Most carbon Emission Trading Systems (ETS) rely on a centralized system to manage the transactional tasks, and are vulnerable to security threats. This article proposes a Blockchain-enabled Distributed ETS (BD-ETS) to improve the security and efficiency ...
Zhuo Hu, Yuhao Du, Congjun Rao, Mark Goh
doaj   +1 more source

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