Results 71 to 80 of about 491,160 (302)

Consensus for the Fip35 folding mechanism? [PDF]

The Journal of Chemical Physics, 2013
Recent advances in computational power and simulation programs finally delivered the first examples of reversible folding for small proteins with an all-atom description. But having at hand the atomistic details of the process did not lead to a straightforward interpretation of the mechanism.
Berezovska, Ganna, Prada, Diego Gracia, Rao, Francesco   +2 more
openaire   +4 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

An Overview and Comparison of Blockchain Consensus Mechanisms [PDF]

International Journal of Networked and Distributed Computing
Blockchain technology has revolutionized digital systems by ensuring trust, transparency, decentralization, and security. However, in the democratic nature of blockchain networks, there is a huge underlying dependency on consensus mechanisms, but the challenges associated with these, such as energy costs, network attacks, preservation of privacy ...
Mutiullah Shaikh, Uffe Kock Wiil, Ali Ebrahimi, Yumna Memon   +3 more
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

LVTM: A lightweight blockchain-based V2G terminal trust management method

CSEE Journal of Power and Energy Systems
As an important part of the smart grid (SG), Vehicle-to-Grid (V2G) has significantly advanced the development of the grid. However, the open nature of V2G system itself and the deployment of charging piles (CPs) increase the difficulty of terminal ...
Jiexiao Yu, Zhibiao Guo, Liying Yu, Ting Yang   +3 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

A model-based online mechanism with pre-commitment and its application to electric vehicle charging

, 2012
We introduce a novel online mechanism that schedules the allocation of an expiring and continuously-produced resource to self-interested agents with private preferences.
Robu, V, Jennings, Nick, Gerding, E, Stein, Sebastian, Jennings, Nicholas R., Gerding, Enrico, Jennings, N, Robu, Valentin, Stein, S   +8 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Consensus-based guidelines for intervention protocols targeting the foot spring mechanism during landing: A modified Delphi study

Objectives To reach consensus of opinion on exercise selection and prescription guidelines for training the energetic function of the foot for landing tasks. Design A modified Delphi design with three rounds of questionnaires. Methods Twenty-eight expert
Bayley, Liz J., Mulligan, Edward P., Nasrallah, Carina M., Fuller, Melanie, Yan, Alycia Fong, Okamura, Kazunori, Brown, Nicholas A.T., Hiller, Claire E., Drysdale, Louise, Castro-Méndez, Aurora, Newman, Phil, Bull, Jerushah J., Strasser, Nicholas, Franettovich, Melinda M., Jeffries, Annie C., Paterson, Kade, Maharaj, Jayishni N., Goldmann, Jan-Peter, Hahn, Michael E., Martínez-Nova, Alfonso, Ridge, Sarah T., Spratford, Wayne A., Radcliffe, Ceridwen R., Farris, Dominic J., Mayes, Susan J., Wang, Lin, Lam, Jason J. Lam   +26 more
core   +1 more source

International Law and Blockchain Governance: Supplements or Competitors

Necmettin Erbakan Üniversitesi Hukuk Fakültesi Dergisi, 2021
Blockchain’s usage is increasing, and the number of possible implications that have been explored and created is mind-boggling. This paper would look at some other potential blockchain implementations in the legal sector, especially in the sense of ...
Vladimir Troitskiy
doaj