Results 91 to 100 of about 4,153,780 (341)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Determinación de factores influyentes sobre una respuesta en un dominio poco estructurado [PDF]

open access: yes, 2001
This report focuses on results obtained from a classification technique applied to time series data in a medical ill-structured The statistical analysis and classification --in ill-structured-- of such data are often inadequate because of the ...
Gibert, Karina   +2 more
core   +1 more source

Concepts for the development of light-weight composite structures for rotor burst containment [PDF]

open access: yes, 1977
Published results on rotor burst containment with single materials, and on body armor using composite materials were used to establish a set of hypotheses about what variables might control the design of a weight-efficient protective device.
Holms, A. G.
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Exploring the consequences of nurses’ involvement in disaster response: findings from a qualitative content analysis study

open access: yesBMC Emergency Medicine
Background The presence of nurses during disasters can lead to many consequences. Understanding the nurses’ experiences of these consequences can provide valuable insights.
Jamileh Farokhzadian   +4 more
doaj   +1 more source

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