Results 141 to 150 of about 4,459,490 (316)
Deflationism, Truth-Aptness and Non-Factualism
Studia Philosophica Estonica, 2008 I will argue that the standard formulation of non-factualism in terms of a denial of truth-aptness is consistent with a version of deflationsim. My line of argument assumes the use conception of meaning.
Massimiliano Vignolo
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Religious Belief, Evidentialism, and Skeptical Theism
Cuestiones Teológicas, 2016 The purpose of the article is to develop a line of argument in favor of a religious belief in the existence of God, in such a way that it is possible to hold that: i) it is a rational belief and ii) it is non-dependent on contingent evidence.
Rafael Felipe Miranda Rojas
doaj
Molinists (still) cannot endorse the consequence argument
International Journal for Philosophy of Religion, 2014 Yishai Cohen
semanticscholar +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Developmental factors as determinants of risk for infections and atopy in childhood
European Respiratory Review, 2005 The nature of the relationship between infections and allergy in children continues to be the subject of vigorous debate, in particular the issue of whether the increased frequency of wheezing respiratory infections in children is a cause or a ...
P. G. Holt
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Another consequence of tanahashi’s argument on best possibility of the grand Furuta inequality
Open Mathematics, 2013 Koizumi Tatsuya, Watanabe Keiichi
doaj +1 more source