Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Hyperbolic P ( Φ ) 2 -model on the Plane. [PDF]
Oh T, Tolomeo L, Wang Y, Zheng G.
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Time-variable training: the goal of competency-based education or a consequence? [PDF]
Kinnear B.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Existence of variational solutions to doubly nonlinear systems in nondecreasing domains. [PDF]
Schätzler L +3 more
europepmc +1 more source
The SGLT2 inhibitor checklist: a comprehensive review of perioperative and acute phase safety management. [PDF]
Deng B, Liu W, Chu Q.
europepmc +1 more source
Optimal Runge approximation for nonlocal wave equations and unique determination of polyhomogeneous nonlinearities. [PDF]
Lin YH, Tyni T, Zimmermann P.
europepmc +1 more source
Plasma exchange following immunoglobulins for Guillain-Barré-Syndrome: a persisting problematic practice? [PDF]
Lucchese G.
europepmc +1 more source

