Results 61 to 70 of about 1,315,168 (284)

Coevolution of parental investment and sexually selected traits drives sex-role divergence

open access: yesNature Communications, 2016
Females tend to invest more than males in caring for offspring, which has been argued to be a consequence of the small initial difference in investment in eggs versus sperm. Here, Fromhage and Jennions formalize this argument mathematically in a model of
Lutz Fromhage, Michael D. Jennions
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Técnica y fetichismo. Apuntes sobre el primer libro de El Capital

open access: yesTheoría Revista del Colegio de Filosofía, 2016
This article shows how technology adopts a fetish nature in the capitalist society, in accordance with the argument presented by Marx in the first book of Capital. We pretend to answer the following issue: is the technology of capital neutral?
Andrea Torres Gaxiola
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Law and economics, consequentialism and legal pragmatism: the influence of Oliver Holmes Jr. [PDF]

open access: yes, 2012
This paper aims to present the similarities and differences between Posner's defense of Law and Economics (LAE) and Holmes' pragmatism. The investigation is centered in the arguments of economic consequences of judicial decisions.
Lima Catão, Adrualdo de
core  

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

On Some Objections to The Deductive Closure of Legal Systems

open access: yesCrítica, 2018
I criticize an argument presented by Pablo Navarro and Jorge Rodríguez (2014) against the conception of legal systems as sets of statements closed under logical consequence.
Hugo R. Zuleta
doaj   +1 more source

Almost sure existence of global weak solutions for super-critical Navier-Stokes equations

open access: yes, 2013
In this paper we show that after suitable data randomization there exists a large set of super-critical periodic initial data, in $H^{-\alpha}({\mathbb T}^d)$ for some $\alpha(d) > 0$, for both 2d and 3d Navier-Stokes equations for which global energy ...
Andrea R. Nahmod   +7 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Deconstructing

open access: yesSAGE Open, 2016
The current article deconstructs Kellerman’s The End of Leadership via postmodernity, epistemology, and worldviews. Despite perceptively synthesizing and diagnosing a host of issues and assumptions that plague the leadership industry, Kellerman’s ...
Robert P. French
doaj   +1 more source

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