Results 131 to 140 of about 3,413,690 (294)
Multiagent modeling of sequential multiunit japanese auctions
, 2018 Features of modeling of auctions are investigated from the point of view of simulation (multiagent) modeling. The characteristic of auctions as object of modeling is resulted.
Yalovets, A.L.
core
Structured Chaos: Unintended Consequences of Over-Modeling
The goal of structuring electronic health data with multiple models has created an interoperability paradox. We analyzed over 140,000 aggregated clinical data elements to identify the root causes of this semantic failure. Key challenges include semantic drift from non-versioned dictionaries, missing traceability from attribute modification, and loss of
Gaudet-Blavignac, Christophe +7 more
openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Impact of dispersion coefficient models on offsite consequence analyses
Nuclear Engineering and TechnologyIn Level 3 probabilistic safety assessment (PSA), accurate modeling of atmospheric dispersion is essential for predicting radionuclide concentrations and radiation doses.
Dakyoung Lee +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Visualization and Modeling Working Group [PDF]
, 2007 During the 2005 Hurricane season, many consequence predictions were available from 36 to 96 hours before landfalls, via the Department of Energy’s Visualization and Modeling Working Group (VMWG).
Dodrill, K. A., Fernandez, S. J.
core
QUANTITATIVE RISK ASSESSMENT OF A CARBON DIOXIDE STORAGE TANK BY USING CONSEQUENCE MODELING AND FUZZY BAYESIAN NETWORKS [PDF]
Salāmat-i kār-i ĪrānBACKGROUND AND AIMS: Given the asphyxiant and odorless nature of carbon dioxide gas, which, while non-toxic, can pose a serious threat to human life at high concentrations, this study aims to conduct a more precise risk assessment. Since the conventional
Mohammadhosein Keyvani Brojeni +5 more
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
بهداشت و ایمنی کار, 2016 Introduction: Although human industrial activities are as a part of efforts to achieve greater prosperity, the risks related to these activities are also expanding.
Mohammad Kamaei +4 more
doaj