Results 171 to 180 of about 3,413,690 (294)

System Modeling in UML with Two-Hemisphere Model Driven Approach

System modeling in an object-oriented manner at the initial stage of software development can be considered as a comprehensive knowledge presentation, which enables the developer practice problem domain (instead of code) to reuse and to share ...
Ņikiforova, Oksana
core  

Analysis of vapor cloud explosion behavior in LPG spherical tanks using multi-energy modeling and machine-learning-based factor assessment. [PDF]

PLoS One
Sarebanzadeh K, Es'haghi M.
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Reframing QSP: AI-Driven Multi-Modal Data as a New Measurement Layer. [PDF]

CPT Pharmacometrics Syst Pharmacol
Knöchel J.
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Toward Understanding Implications of AI-Powered Intelligent Transportation Systems on Risk Research and Practice. [PDF]

Risk Anal
Thekdi S, Santos J, Tatar U, Chatterjee S.   +3 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

DECANT: decoupling mechanism from context in single-cell drug perturbation representation. [PDF]

Bioinformatics
Qi R, Teng W, Yang X, Cheng Y, Shaytan AK, Liu B.   +5 more
europepmc   +1 more source

A Model of Antecedents and Consequences of Moonlighting

پژوهش‌های مدیریت عمومی
Abstract Despite the widespread phenomenon of moonlighting in the uncertain and complex environment of the labor market, there is still no definite theoretical consensus on its antecedents and consequences. In this sense, the aim of the present research is to provide a model for moonlighting in the form of identifying the precedents and their ...
Nasim Afshar-kaveh, Alireza Koushkie, Mirali Seyed Naghavi, Saeed Zarandi   +3 more
openaire   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source