Results 51 to 60 of about 333,204 (306)

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

open access: yesAdvanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu   +34 more
wiley   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

open access: yesAdvanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel   +11 more
wiley   +1 more source

Corruption in the system of threats to economic security

open access: yesПутеводитель предпринимателя, 2020
In modern conditions the corruption has all the necessary features for the recognition of its potential threat to state security, since corruption affects the General interests of the society. The authors consider the problem of corruption as a threat to
E. I. Kuznetsova, E. V. Borisova
doaj  

Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics

open access: yesAdvanced Science, EarlyView.
Integrated computational‐biological programming enables secure in vivo data storage by generating code tables from either genomes or gene regulatory networks, expanding the encryption key space by over 100 orders of magnitude. Storing code tables within synthetic genes, genomes, or gene regulatory networks adds an additional layer of security by ...
Jiaxin Xu   +9 more
wiley   +1 more source

Equilibrium Consequences of Corruption on Firms: Evidence from China’s Anti-Corruption Campaign

open access: yes, 2020
We use China's recent anti-corruption campaign as a natural experiment to examine the (market expected) equilibrium consequences of (anti-)corruption. We argue that the announcement of inspections of provincial governments by the Central Commission for Discipline Inspection (CCDI) on May 17, 2013 represents a significant departure of past norms of anti-
Haoyuan Ding   +3 more
openaire   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

open access: yesAdvanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen   +7 more
wiley   +1 more source

Corruption in America [PDF]

open access: yes
We use a data set of federal corruption convictions in the U.S. to investigate the causes and consequences of corruption. More educated states, and to a less degree richer states, have less corruption.
Edward L. Glaeser, Raven Saks
core   +3 more sources

Corrupção e seleção por consequências: uma análise comportamental

open access: yesPsicologia: Teoria e Pesquisa, 2018
Resumo A corrupção é um fenômeno global. Sob os parâmetros teóricos e metodológicos da Análise Comportamental da Cultura, constitui nosso objetivo compor um panorama descritivo-explicativo da corrupção como prática cultural, mediante uma análise ...
Kester Carrara, Diego Mansano Fernandes
doaj   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

open access: yesAdvanced Science, EarlyView.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang   +15 more
wiley   +1 more source

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