Results 41 to 50 of about 699,751 (248)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Scenography of Serpotta Stuccoes Revisited - Material and Form
Conservation Science in Cultural Heritage, 2015 The material that lies beneath the smooth shining surface of the stuccoes of the Serpotta family who used to work in Sicily from 1670 to 1730, has been thoroughly studied in previous papers, disclosing the deep, albeit empirical, knowledge of materials ...
Salvatore Barba +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Conservation Science in Cultural Heritage, 2012 The reduction of greenhouse gas emissions in buildings offers one of the most promising opportunities for developed and developing countries to cooperate in achieving the realization of significant energy efficiency improvements.
Marija S. Todorović
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Carbonatogenesis: microbial contribution to the conservation of monuments and artwork of stone
Conservation Science in Cultural Heritage, 2012 Over the last few decades there has been increasing global concern over the deterioration of historical monuments and stone works of art. It has posed a big challenge for the archaeologist, geobiologists and bioconservators and consequently encouraged ...
Swaranjit S. Cameotra, Tikam C. Dakal
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Conservation Science in Cultural Heritage, 2018 The built heritage of the 1950s French colonial era represents the complexity of the hybrid cultural identity bequeathed by history but attracts minimal interest and consideration as an accepted local heritage. This research focuses on the opportunities
Loubna Kara Mostefa, Kheira Tabet Aoul
doaj +1 more source