Results 41 to 50 of about 967,378 (249)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Conservation Science in Cultural Heritage, 2012 The reduction of greenhouse gas emissions in buildings offers one of the most promising opportunities for developed and developing countries to cooperate in achieving the realization of significant energy efficiency improvements.
Marija S. Todorović
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Carbonatogenesis: microbial contribution to the conservation of monuments and artwork of stone
Conservation Science in Cultural Heritage, 2012 Over the last few decades there has been increasing global concern over the deterioration of historical monuments and stone works of art. It has posed a big challenge for the archaeologist, geobiologists and bioconservators and consequently encouraged ...
Swaranjit S. Cameotra, Tikam C. Dakal
doaj +1 more source
Conservation value of national forest roadless areas [PDF]
, 2020 McKinley J. Talty +3 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Conservation Science in Cultural Heritage, 2018 The built heritage of the 1950s French colonial era represents the complexity of the hybrid cultural identity bequeathed by history but attracts minimal interest and consideration as an accepted local heritage. This research focuses on the opportunities
Loubna Kara Mostefa, Kheira Tabet Aoul
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Generalized symmetries and conservation laws of (1 + 1)-dimensional Klein–Gordon equation [PDF]
, 2020 Stanislav Opanasenko, Roman O. Popovych
openalex +1 more source