Results 51 to 60 of about 729,067 (269)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Carbonatogenesis: microbial contribution to the conservation of monuments and artwork of stone

Conservation Science in Cultural Heritage, 2012
Over the last few decades there has been increasing global concern over the deterioration of historical monuments and stone works of art. It has posed a big challenge for the archaeologist, geobiologists and bioconservators and consequently encouraged ...
Swaranjit S. Cameotra, Tikam C. Dakal
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Integrated Bicultural Referent of the Built Colonial Heritage: Social Housing Models in Oran (1954–1958), Algeria

Conservation Science in Cultural Heritage, 2018
The built heritage of the 1950s French colonial era represents the complexity of the hybrid cultural identity bequeathed by history but attracts minimal interest and consid­eration as an accepted local heritage. This research focuses on the opportunities
Loubna Kara Mostefa, Kheira Tabet Aoul
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Conservation = Conservation

, 1988
African freshwater fishes are endangered by over exploitation of live fish for aquarists and for exports, intensive fishing of species with low resilience, introduction of exotic species, pollution, general environmental modification by man. Therefore, to ensure conservation to fish species, it is necessary to increase basic knowledge in order to ...
Daget, Jacques, Gaigher, I.C., Ssentongo, G.W.   +2 more
openaire   +1 more source

Heritage Conservation and Urban Landscaping of Ancient Pan Pool Neighborhood, Qufu: a Historical and Indigenous Perspective

Conservation Science in Cultural Heritage, 2014
Gu Pan Pool neighborhood got its name because of Gu Pan Chi, (古泮池，the ancient Pan Pool), located in the southeastern part of Confucius’ birthplace, Qufu, the birth place of Confucius with a history of 3000 year.
Yingchun Zhang, Zongjie Wu
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

“What is convenient” or art between economics and politics

Conservation Science in Cultural Heritage, 2014
Art, as a set of signs and techniques, has always been one of the most important modes of transfiguration in the world. It therefore has a political function: it is not a reproduction, but a questioning of reality.
Luigi Canetti
doaj   +1 more source