Results 51 to 60 of about 967,378 (249)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Conservation Science in Cultural Heritage, 2014 Gu Pan Pool neighborhood got its name because of Gu Pan Chi, (古泮池，the ancient Pan Pool), located in the southeastern part of Confucius’ birthplace, Qufu, the birth place of Confucius with a history of 3000 year.
Yingchun Zhang, Zongjie Wu
doaj +1 more source
Biogeographic Overview of Ulmaceae: Diversity, Distribution, Ecological Preferences, and Conservation Status [PDF]
, 2021 Yann Fragnière +5 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
“What is convenient” or art between economics and politics
Conservation Science in Cultural Heritage, 2014 Art, as a set of signs and techniques, has always been one of the most important modes of transfiguration in the world. It therefore has a political function: it is not a reproduction, but a questioning of reality.
Luigi Canetti
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The individuation of Cultural Heritage owned by the State and by non profit private bodies
Conservation Science in Cultural Heritage, 2004 The individuation of the cultural heritage is the first step to be carried out before subjecting the cultural heritage to the legal preservation regime.
Nicola Aicardi
doaj +1 more source
Effect of Locally Adapted Conservation Tillage on Runoff, Soil Erosion, and Agronomic Performance in Semiarid Rain-Fed Farming in Ethiopia [PDF]
, 2023 Laike Kebede +5 more
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source