Results 71 to 80 of about 101,898 (241)
PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li +10 more
wiley +1 more source
The carbon footprint of Conservation Agriculture
Proponents of Conservation Agriculture (CA) believe that by not tilling the soil, climate-friendly agriculture is achieved by reducing greenhouse gas emissions from agriculture and by storing atmospheric carbon in the soil.
Maik Freitag +2 more
doaj +1 more source
SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo +14 more
wiley +1 more source
The main aim of this study was to investigate the potential of encouraging intention to use conservation agriculture technologies to create sustainable social and psychological changes in agricultural communities.
Naser Valizadeh +2 more
doaj +1 more source
Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng +19 more
wiley +1 more source
Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang +9 more
wiley +1 more source
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma +22 more
wiley +1 more source
Conservation agriculture is an innovative approach based on minimal soil disturbance, soil cover with crop residues, and crop rotation, which increases the biodiversity of soil macrofauna thus contributing to nutrient cycling and soil aggregation.
Anicet Gbèblonoudo Dassou +8 more
doaj +1 more source
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source

