Results 241 to 250 of about 342,303 (293)

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Virginia Red-cockaded Woodpecker Conservation Plan

open access: yes, 2007
Harding, S. R., Watts, B. D.
core  

Zoo Conservation Biology

open access: yes, 2011
In the face of ever-declining biodiversity, zoos have a major role to play in species conservation. Written by professionals involved in in situ conservation and restoration projects internationally, this is a critical assessment of the contribution of zoos to species conservation through evidence amassed from a wide range of sources.
Fa, JE, Funk, SM, O’Connell, D
openaire   +3 more sources

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