Results 41 to 50 of about 291,874 (245)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Abstrak: Penelitian ini bertujuan untuk mendeskripsikan kompetensi mahasiswa menguasai dan mengaplikasikan konsep konservasi literasi biodiversitas, yaitu dengan penerapan program perkuliahan Biologi Konservasi Berbasis Kearifan Lokal (BKBKL) yang ...
Suroso Mukti Leksono +2 more
doaj +1 more source
Ecologists, outdoor professionals and the public work and play in lands with complex histories. Part of decolonizing our professional and recreational practices is to expose settler colonial biases and recognize the histories of colonized lands and the ...
Bonnie M. McGill +5 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Natural canopy bridges effectively mitigate tropical forest fragmentation for arboreal mammals
Linear infrastructure development and resulting habitat fragmentation are expanding in Neotropical forests, and arboreal mammals may be disproportionately impacted by these linear habitat clearings. Maintaining canopy connectivity through preservation of
Tremaine Gregory +4 more
doaj +1 more source
Context Asian elephant numbers are declining across much of their range driven largely by serious threats from land use change resulting in habitat loss and fragmentation.
A. N. Chan +10 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
From a natural sciences perspective, efforts directed at the conservation of biodiversity are based upon what is known as conservation biology. Given its epistemological assumptions, conservation biology faces obstacles in the incorporation of wisdom ...
Jorje Ignacio Zalles
doaj +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Reintroduced animals—especially those raised in captivity—are faced with the unique challenge of navigating a wholly unfamiliar environment, and often make erratic or extensive movements after release.
M. M. Majaliwa +15 more
doaj +1 more source

