Results 71 to 80 of about 3,611,494 (288)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

PENGEMBANGAN NILAI KARAKTER KONSERVASI BERBASIS PEMBELAJARAN

Jurnal Penelitian Pendidikan, 2012
Department of Biology, State University of Semarang (Unnes) is beeing committed to implement competency and conservation-based curriculum since the academic year 2012/2013.
Saiful Ridlo, Andin Irsadi
doaj  

Museum genomics provide insight into the extinction of a specialist North American warbler species

Scientific Reports
Museum genomics provide an opportunity to investigate population demographics of extinct species, especially valuable when research prior to extinction was minimal.
Paige A. Byerly, Anna M. Kearns, Andreanna Welch, Margad-Erdene Ochirbat, Peter P. Marra, Amy Wilson, Michael G. Campana, Robert C. Fleischer   +7 more
doaj   +1 more source

Scale-insensitive estimation of speed and distance traveled from animal tracking data

Movement Ecology, 2019
Background Speed and distance traveled provide quantifiable links between behavior and energetics, and are among the metrics most routinely estimated from animal tracking data. Researchers typically sum over the straight-line displacements (SLDs) between
Michael J. Noonan, Christen H. Fleming, Thomas S. Akre, Jonathan Drescher-Lehman, Eliezer Gurarie, Autumn-Lynn Harrison, Roland Kays, Justin M. Calabrese   +7 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Herpetological Conservation & Biology

, 2012
In 2006, the Herpetological Conservation & Biology journal was started to offer a place for manuscripts in the field "that were descriptive or natural history oriented." This journal publishes original peer-reviewed research, reviews, and ...

core  

Can methods applied in medicine be used to summarize and disseminate conservation research? [PDF]

, 2004
To ensure that the best scientific evidence is available to guide conservation action, effective mechanisms for communicating the results of research are necessary.
Lindenmayer, David B, Lindenmayer, D B, Maindonald, J, Salisbury, Janet G, Ioan Fazey, Robert Douglas, Fazey, Ioan, Janet G. Salisbury, David B. Lindenmayer, Douglas, R, Fazey, Ioan Raymond Albert, Maindonald, John, Salisbury, J G, Douglas, Robert, John Maindonald, Douglas, Robert M   +15 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Markers of fertility in reproductive microbiomes of male and female endangered black-footed ferrets (Mustela nigripes)

Communications Biology
Reproductive microbiomes contribute to reproductive health and success in humans. Yet data on reproductive microbiomes, and links to fertility, are absent for most animal species.
Sally L. Bornbusch, Alexandra Bamford, Piper Thacher, Adrienne Crosier, Paul Marinari, Robyn Bortner, Della Garelle, Travis Livieri, Rachel Santymire, Pierre Comizzoli, Michael Maslanka, Jesús E. Maldonado, Klaus-Peter Koepfli, Carly R. Muletz-Wolz, Alexandra L. DeCandia   +14 more
doaj   +1 more source