Results 61 to 70 of about 644,259 (331)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Spatiotemporal Distribution Patterns and Conservation Priorities of Gymnosperms With Different Leaf Shapes in China Under Climate Change

Ecology and Evolution
Leaf morphology is one of the important indicators for studying the response of plants to climate change. Gymnosperms play a crucial role in maintaining biodiversity and ecosystem stability in China. However, the geographical and altitudinal distribution
Jinyi Fu, Wenjie Song, Chuncheng Wang, Xiaolong Jiang, Xiangbao Shen, Rong Yi   +5 more
doaj   +1 more source

Key Components and Best Practices for Environmental Impact Assessments [PDF]

, 2016
New and emerging activities pose risks to the conservation and sustainable development of ABNJ in the absence of prior assessment, and remain a significant gap under UNCLOS.
Duncan E. J. Currie
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Spatial Distribution and Conservation Prioritization of Medicinal Gymnosperms in China Using an Optimal Set‐Cover Approach

Ecology and Evolution
To elucidate the geographical distribution patterns and hotspots of medicinal gymnosperms in China, providing a scientific basis for formulating conservation strategies for this group, we compiled 17,999 occurrence records for 148 medicinal gymnosperm ...
Lisi Hai, Xinyi Wang, Yuchang Yang, Rui Shu, Yanqin Xu, Guibing Lin, Lihua Dong, Xiaobo Zhang, Zhangjian Shan   +8 more
doaj   +1 more source

Conservation of Three-Dimensional Helix-Loop-Helix Structure through the Vertebrate Lineage Reopens the Cold Case of Gonadotropin-Releasing Hormone-Associated Peptide

Frontiers in Endocrinology, 2017
GnRH-associated peptide (GAP) is the C-terminal portion of the gonadotropin-releasing hormone (GnRH) preprohormone. Although it was reported in mammals that GAP may act as a prolactin-inhibiting factor and can be co-secreted with GnRH into the ...
Daniela I. Pérez Sirkin, Daniela I. Pérez Sirkin, Anne-Gaëlle Lafont, Nédia Kamech, Gustavo M. Somoza, Paula G. Vissio, Paula G. Vissio, Sylvie Dufour   +7 more
doaj   +1 more source

Electrostatic Patch Effect in Cylindrical Geometry. I. Potential and Energy between Slightly Non-Coaxial Cylinders

, 2010
We study the effect of any uneven voltage distribution on two close cylindrical conductors with parallel axes that are slightly shifted in the radial and by any length in the axial direction. The investigation is especially motivated by certain precision
Alexander S Silbergleit, Buchman S, Buchman S, Darling T W, Godin Yu A, Godin Yu A, Keiser G M, Lebedev N N, Lebedev N N, Lockhart J M, Mester J, Prince T, Rossi F, Speake C C, Valerio Ferroni, Worden P W, Yerofeenko V T   +16 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

New Hybrid Protected Lands Layer for Vermont Conservation Design Analysis (February 2019) [PDF]

, 2019
This shapefile (.shp) is a hybrid of the March 2017 Edition of the Vermont Center for Geographic Information\u27s (VCGI) Vermont Protected Lands Database (VPLD), the Vermont Land Trust\u27s February 2019 Protected Lands database, and The Nature ...
D\u27Amato, Anthony W, Loeb, Carolyn D
core   +1 more source