Results 151 to 160 of about 1,068,650 (333)
Conservation of Some Natural Resources in Ganeshpuri, Thane Maharashtra, India [PDF]
, 2020 Rohan Bhagat
openalex +1 more source
Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma
Advanced Science, EarlyView.IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang +16 more
wiley +1 more source
Academic Output in Smart Agriculture with Conservation of Natural Resources : Indian vs. Global Scenario [PDF]
, 2020 NK Prasanna Kumari +2 more
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A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules
Advanced Science, EarlyView.Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang +6 more
wiley +1 more source
Advanced Science, EarlyView.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
South Carolina Wildlife, March-April 1999 [PDF]
, 1999 The South Carolina Wildlife Magazines are published by the South Carolina Department of Natural Resources who are dedicated to educating citizens on the value, conservation, protection, and restoration of South Carolina's wildlife and natural resources ...
Conservation, Education, and Communications Division of the South Carolina Department of Natural Resources
core
Advanced Science, EarlyView.Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong +19 more
wiley +1 more source
South Carolina Wildlife, January-February 2000 [PDF]
, 2000 The South Carolina Wildlife Magazines are published by the South Carolina Department of Natural Resources who are dedicated to educating citizens on the value, conservation, protection, and restoration of South Carolina's wildlife and natural resources ...
Conservation, Education, and Communications Division of the South Carolina Department of Natural Resources
core
Integrating Participatory Resource Mapping and Geographic Information Systems in Forest Conservation and Natural Resources Management in Cameroon: A Methodological Guide [PDF]
, 2003 P. Mbile, A. Degrande, David Tiku Okon
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Modeling Control of Invasive Fire Ants by Gene Drive
Advanced Science, EarlyView.The fire ant Solenopsis invicta is characterized by exceptional invasive capabilities, rendering conventional control ineffective. Here, we explore the use of homing suppression gene drive in fire ants by developing a spatially explicit model. Overall, these results show that target population suppression requires an extended time scale, but that gene ...
Yiran Liu +3 more
wiley +1 more source