Results 161 to 170 of about 1,057,758 (327)

Inhabitant Evaluation Structure for Accessible Natural Resources and Conservation Measures:

, 2012
Go Tamura, Tomo Onizuka, Akihiro Katsura, Toshikazu Urade   +3 more
openalex   +2 more sources

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

The government policy on the conservation of natural resources and ecosystems in Kuningan, Indonesia [PDF]

, 2019
Suwari Akhmaddhian, H Hartiwiningsih, I G A K R Handayani, Erga Yuhandra, Yuhandra, H Budiman E, Diding Rahmat, O Syafrudin   +7 more
openalex   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source

Genetic diversity of Syagrus cearensis Noblick in natural populations: implications for conservation of genetic resources

, 2022
Abidã Gênesis da Silva Neves, Luciana Gomes Pinheiro, Cristiane Gouvêa Fajardo, Fábio de Almeida Vieira   +3 more
openalex   +2 more sources

Mapping Natural Product Biosynthetic Hotspots: Prioritizing Conservation for Medicinal Resources [PDF]

, 2023
Muhamad Fahmi, Kojiro Takanashi, Yusuke Kakei, Yasuhiro Kubota, Keiichiro Kanemoto   +4 more
openalex   +1 more source

Transient Antiskyrmion‐Mediated Topological Transitions in Isotropic Magnets

Advanced Science, EarlyView.
A transient antiskyrmion‐mediated pathway that drives repeated stripe‐to‐skyrmion transitions is revealed, producing a net increase in topological charge in isotropic Dzyaloshinskii–Moriya interaction films. Experiments and simulations identify the antiskyrmion as a metastable excitation, enabling stochastic bitstream generation for probabilistic ...
Bingqian Dai, Tianyi Wang, Albert Lee, Shijie Xu, Zhongjian Bian, Xinyue Zhu, Puyang Huang, Aadi Chaturvedi, Yaochen Li, Yang Cheng, Qingyuan Shu, Haoran He, Hanshen Huang, Lixuan Tai, Kin Wong, Jinbo Yang, Anjan Soumyanarayanan, Zhaochu Luo, Kang L. Wang   +18 more
wiley   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Genome-Wide SNP Data and Species Distribution Modeling Reveal Population Structure and Conservation Implications of <i>Primula wilsonii</i> (Primulaceae). [PDF]

Ecol Evol
Xie Y, Jin X, Yang G, Lu D, Zhang C, Zhang X, Jiang X.   +6 more
europepmc   +1 more source

Conservation of Natural Resources [PDF]

Nature, 1958
openaire   +1 more source