Results 241 to 250 of about 1,057,758 (327)

Policies and Practices for the conservation of natural resources during infrastructure development in Nepal

Diwat Kumar Shrestha, B. M. Praveen
openalex   +2 more sources

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Economic valuation of farmland using natural-attribute-based indicators: A case study of Hefei, China. [PDF]

PLoS One
Yuan L, Fan X, Feng B.
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

The first report on complete mitochondrial genome of <i>Murina yushuensis</i> (Chiroptera: Vespertilionidae) and its phylogenetic analysis. [PDF]

Mitochondrial DNA B Resour
Shi H, Huang T, Fan X, Wang X, Yu W, Fu X, Wu Y.   +6 more
europepmc   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

First Morphological Description of Larvae of Two Endemic Goby Species from Chinese Waters. [PDF]

Animals (Basel)
Liu S, Zeng Y, He Y, Zheng B, He H, Liu L, Zhang C, Yao W, Zhong J.   +8 more
europepmc   +1 more source

Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance

Advanced Science, EarlyView.
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang, Quan Li, Man Shi, Marcio F.A. Leite, Xinli Chen, Eiko E. Kuramae, Viviane Cordovez, Tingting Cao, Chenglei Zhu, Libin Zhou, Wenjuan Yu, Zhiyao Tang, Changhui Peng, Xinzhang Song   +13 more
wiley   +1 more source

Range-wide assessment of habitat suitability for jaguars using multiscale species distribution modelling. [PDF]

Sci Rep
Alvarenga GC, Sartor CC, Cushman SA, Zimmermann A, Srbek-Araujo AC, Mendes-Oliveira AC, Harmsen B, De Angelo C, Esteves CF, de Campos CB, Polli DJ, Viana DFP, Gräbin DM, Donadio E, Ramalho EE, Payán E, Azevedo FCC, Palomares F, Powell GVN, Ceballos G, Porfirio G, Zarza H, Cassaigne I, Bogoni JA, Sena L, Maranhão L, de Brito MRM, Tobler MW, Wiig Ø, Foster RJ, Sampaio R, Nuñez R, Morato RG, Boron V, Moreno WHA, Malhi Y, Macdonald DW, Kaszta Ż.   +37 more
europepmc   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source