Results 221 to 230 of about 200,820 (302)

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Bridging genetic knowledge gaps in a biodiversity hotspot through conservation training. [PDF]

Bioscience
Enguídanos García A, Cuesta-Porta V, Abrego L J, Almanza M, Alvelo Villegas KZ, Antaneda H J, Bonner L, Carpintero OJ, Collado GN, Córdoba González D, Díaz Vergara M, Guerra-Lima ZI, Noriega JD, de León Herrera DS, Domingo AI, Durán O, Garrido-Trujillo A, González Y, Justo Riverol SC, Guerrero Romero A, León Correoso N, Molina LEP, Montalvo E, Pérez-González CM, Rivera M, Vásquez Acosta JL, Vásquez M, Vega-Atencio A, Zhuo W, Galià-Camps C.   +29 more
europepmc   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

Ethnobotanical assessment of wild edible plants and indigenous knowledge in Tegedie District, Ethiopia. [PDF]

J Ethnobiol Ethnomed
Goshe A, Masresha G, Asnakew M, Awoke A.
europepmc   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Mapping Conservation Biological Control and IPM Research (2000-2025): A Bibliometric Analysis of Natural Enemies and Habitat Management. [PDF]

Insects
Hyder M, Ullah F, Basit A, Haq IU, Mustapha T, Nisa ZU, Cai X, Liu H, Hou Y.   +8 more
europepmc   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

Advanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li, Chun‐Hui Zhang, Yong Wang, Cheng‐Yuan Li, Da‐Rong Wen, Xi Xia, Liang Zhou, Wei‐Ping Qian, Qing‐Yuan Sun, Chang‐Zhong Li   +9 more
wiley   +1 more source

A Multi-Factor Habitat Suitability Model for Asian Elephants in the Greater Mekong Subregion: Effects of Vegetation and Climate. [PDF]

Ecol Evol
Li C, Wang X, Qiang Z, Tang Y, Yang S, Luo C, Tu X, Zhang S, Xia Y, Zhang L.   +9 more
europepmc   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

China's forests host a vast, previously unquantified population of old trees. [PDF]

Natl Sci Rev
Ren Y, Cheng K, Zhang J, Xiang T, Xu Y, Yang S, Li Y, Fang O, Yang Q, Chen A, Li Y, Cheng Z, Zhang H, Xu G, Yang Y, Guo Q.   +15 more
europepmc   +1 more source