Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng +12 more
wiley +1 more source
Botho: A cultural framework for resilient human-wildlife coexistence in Botswana. [PDF]
Bahetoleng O, Stronza A.
europepmc +1 more source
Farmers' organizations in Nnindye, Uganda: building social capital for the conservation of natural resources [PDF]
Canwat, Vincent +4 more
core
Through a systematic and comprehensive analysis of the environmental impacts for the emerging MXene synthesis pathways, this study presents process transformation and optimization opportunities for low‐carbon MXene production from laboratory to industrial scales.
Yushuai Huang +6 more
wiley +1 more source
China's National Botanical Gardens: An innovative model to support global biodiversity conservation and sustainable development. [PDF]
He T +10 more
europepmc +1 more source
Balancing land use for conservation, agriculture, and renewable energy. [PDF]
Brock C +19 more
europepmc +1 more source
High-quality surrounding landscapes mitigate avian extirpations from forest remnants. [PDF]
Bueno AS +57 more
europepmc +1 more source
The FORGENIUS Genomic Resources: New Genotyping Tools and Genomic Data for 23 Forest Tree Species and Their Genetic Conservation Units. [PDF]
Pinosio S +14 more
europepmc +1 more source
Energy consumption features, correlative factors, and management strategies of tertiary hospitals across various climate zones in Jiangsu, China. [PDF]
Ni X, Pan Y, Peng L, Li X, Xu H.
europepmc +1 more source
Human-Wildlife Interactions: Cultural Sensitivities and Perspectives Influence the Conservation of the Philippine Brown Deer (<i>Rusa marianna</i> Desmarest, 1822). [PDF]
Villegas JP +3 more
europepmc +1 more source

