Results 31 to 40 of about 771,843 (288)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Managing agricultural phosphorus to minimize water quality impacts

Scientia Agricola, 2016
Eutrophication of surface waters remains a major use-impairment in many countries, which, in fresh waters, is accelerated by phosphorus (P) inputs from both point (e.g., municipal waste water treatment plants) and nonpoint sources (e.g., urban and ...
Andrew Sharpley
doaj   +1 more source

Assessing performance of conservation-based Best Management Practices: Coarse vs. fine-scale analysis [PDF]

, 2010
Background/Questions/Methods Animal agriculture in the Spring Creek watershed of central Pennsylvania contributes sediment to the stream and ultimately to the Chesapeake Bay.
Denise A. Piechnik, Sarah C. Goslee, Tamie L. Veith   +2 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Heritage valuing and the challenge of remoteness: The case of the rock-hewn church of Nazugn Mariam, Meket District, Northern Ethiopia

Cogent Social Sciences
This study aims to explore the values and conservation threats of Nazugn Mariam monolithic rock-hewn church, a typical instance not only show the country’s long forgotten, ill-considered and endangered ancient rock-hewn churches in the rural areas but ...
Tsegaye Ebabey Demissie
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Multi-Decadal Nutrient Management and Trends in Two Catchments of Lake Okeechobee

Resources
 Despite years of efforts to improve water quality, harmful algal blooms remain a chronic phenomenon, with devastating environmental, economic, and social impacts in many regions worldwide.
Rachael Z. Cooper, Sarina J. Ergas, Mahmood Nachabe   +2 more
doaj   +1 more source

Linking agrobiodiversity and culture through the adoption of agroforestry practices: The Agroforestry Indigenous Agents [PDF]

, 2020
Agroforestry is the result of a dialectical relationship between humans and the environment, capable of increasing agricultural biodiversity. In the Brazilian Amazon region, Agroforestry Indigenous Agents have been disseminating these practices through ...
Fajardo Cavalcanti de Albuquerque, Marcia
core  

New Hope for the Oceans: Engaging Faith-Based Communities in Marine Conservation [PDF]

, 2017
Science alone cannot protect the oceans and their biological diversity. Whereas, scientists can identify problems and empirical steps toward their resolution, support for research, problem solving, and implementation of solutions must come from societal ...
Schaefer, Jame
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source