Results 61 to 70 of about 2,436,716 (244)

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

Environmental Bridgebuilding: Connecting People Through Nature Conservation. The Example of the Barn Owl

Ecology and Evolution
Psychologists have long known that contact with and exposure to so‐called outgroup members can help overcome separation, including those resulting from entrenched conflicts.
Christine Mohr, Philippe Le Billon, Yossi Leshem, Vasileios Bontzorlos, Alexandre Roulin   +4 more
doaj   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

Advanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo, Ruijin Xie, Hua Xu, Xue Xiao, Wei Xiao, Qiyang Pan, Shengjie Xu, Li Liu, Zeliang Xiao, Yue Zhou, Chenyu Sun, Yu Wu, Yueying Liu   +12 more
wiley   +1 more source

Voluntary Collective Action to Address Growing Agricultural Challenges in Two Countries: Experimental Insights and Commonalities

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT We conducted two framed field economic experiments with citrus farmers in Florida, United States and soybean farmers in Argentina to investigate their willingness to coordinate pest and weed management efforts. Despite the contrast between these two agricultural contexts, we find striking behavioral commonalities.
Ariel Singerman, Sergio H. Lence
wiley   +1 more source

The practice and promise of private land conservation

Ecology and Society, 2018
In many countries around the globe, private freehold lands cover large areas. Conservation on these private lands, next to statutory protected areas, promises to play a critical role in efforts for reaching internationally agreed environmental protection
Michael Drescher, Jacob C. Brenner
doaj   +1 more source

Regional Differences in U.S. Consumer Preferences for Native Woody Shrubs With Varying Aesthetic Characteristics

Agribusiness, EarlyView.
ABSTRACT Native plants offer a variety of aesthetic (e.g., fall colour, fruit, flowers) and functional benefits (e.g., pollinator friendly, wildlife friendly, water management). How these benefits influence consumer choice and perceived value of native versus introduced plants is not well understood.
Alicia Rihn, Ariana P. Torres, Sue Barton, Bridget K. Behe   +3 more
wiley   +1 more source

Living with elephants: A case study from Kavango‐Zambezi Transfrontier Conservation Area in Zimbabwe

People and Nature
The Kavango‐Zambezi Transfrontier Conservation Area (KaZa TFCA) is home to one of the largest populations of African savanna elephants (approximately 227,000), a species iconic for ecological balance but also a major driver of human–elephant conflict ...
Muhammad Faizan Usman, Martin Reinhardt Nielsen, Sébastien Le Bel, Maxwell Phiri, Patrice Grimaud   +4 more
doaj   +1 more source

Exploring Genetic and Biological Interconnections Between Neuroticism, Psychological Distress, Insomnia, and C‐Reactive Protein: Insights From the UK Biobank

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychobehavioral and physical health traits often co‐occur. Although previous studies have identified associations between neuroticism, psychological distress, insomnia, and inflammatory biomarkers such as C‐reactive protein (CRP), it remains unclear whether there is a genetic basis to these associations, and which biological pathways are ...
Lydia M Li, Nina Adler, Cristina L. Abbatangelo, Mark Wade, Esteban J. Parra   +4 more
wiley   +1 more source

La psychologie de la conservation de la biodiversité : le maillon faible dans les stratégies et les interventions des acteurs des territoires ?

VertigO
The major and ever-increasing challenges facing the world's biodiversity require us to question the effectiveness of the public policies, strategies and actions undertaken to date in the field of conservation.
Arnaud Collin
doaj   +1 more source