Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
From Nanoparticles to Gels: A Breakthrough in Art Conservation Science. [PDF]
Langmuir, 2023 Chelazzi D, Baglioni P.
europepmc +1 more source
Consecration and Conservation; Walden Pond as a Sacred Site [PDF]
, 2002 This essay explores the dynamic interplay between religion, science, and the environment by focusing on Henry David Thoreau\'s consecration of Walden Pond and the subsequent history of the site \'s conservation as a natural and cultural shrine.
Page, Torvis
core
Gauge Theory for the Rate Equations: Electrodynamics on a Network
, 2007 Systems of coupled rate equations are ubiquitous in many areas of science, for example in the description of electronic transport through quantum dots and molecules.
A. E. Siegman +13 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Human mediation should be a non‐factor in hybridization and conservation
Conservation Science and PracticeHybridization by introgression (“hybridization”) is a complex topic in conservation. Many conservation decision‐makers are concerned about hybridization by introgression because it may threaten species persistence or local phenotypes, among other ...
Derek Halm
doaj +1 more source
Historical issues: the basis of Conservation Science and Conservator-Restorer training
Conservar Património, 2016 The gradual integration of science into the museum and the strengthening of the collaboration between the conservators-restorers, the conservation scientists, and the curators describe the early history of the Conservation Science.
Yacy-Ara Froner
doaj +1 more source
Connectivity modelling in conservation science: a comparative evaluation. [PDF]
Sci Rep, 2022 Unnithan Kumar S, Cushman SA.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A systematic review of animal personality in conservation science. [PDF]
Conserv Biol, 2023 MacKinlay RD, Shaw RC.
europepmc +1 more source