Results 111 to 120 of about 6,505,732 (343)

Climate change, forest conservation and science: A case study of New Zealand, 1860s-1920 [PDF]

open access: yes, 2009
To most of its European settlers, New Zealand was a land blessed by Providence. A temperate climate and year-round rainfall, easy availability of land and myriad work opportunities attracted many to the new colony.
Beattie, James John
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Making conservation science more reliable with preregistration and registered reports

open access: yesConservation Biology, 2019
Article impact statement: Preregistration and registered reports are good for researchers, good for research, and good for the reliability of science as a whole. This article is protected by copyright. All rights reserved.
T. Parker   +2 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Introducing Relational Values as a Tool for Shark Conservation, Science, and Management

open access: yesFrontiers in Marine Science, 2019
Relational values are values that arise from a relationship with nature, encompassing sense of place, feelings of well-being (mental and physical health), and cultural, community, or personal identities.
R. Skubel   +2 more
semanticscholar   +1 more source

Minimizing Vessel Strikes to Endangered Whales: A Crash Course in Conservation Science and Policy [PDF]

open access: yes, 2009
The North Atlantic right whale is one of the most endangered of all large whales: about 350-400 individuals remain. Species recovery is, in part, contingent on reducing vessel-strike mortality.
Brown, Moira W, Wiley, David N
core   +1 more source

Age and growth of Zapteryx brevirostris (Elasmobranchii: Rhinobatidae) in southern Brazil [PDF]

open access: yes, 2018
Age and growth studies are fundamental to successful fisheries management. Zapteryx brevirostris (Muller & Henle, 1841) is distributed off the Brazilian continental shelf and this species is assessed as "Vulnerable" in the Red List of the International ...
Carmo, Wanessa P. D.   +2 more
core   +4 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

A methodological guide to using and reporting on interviews in conservation science research

open access: yes, 2018
Interviews are a widely used methodology in conservation research. They are flexible, allowing in‐depth analysis from a relatively small sample size and place the focus of research on the views of participants.
J. Young   +13 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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