Results 51 to 60 of about 28,629,234 (254)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Cultural valuation and biodiversity conservation in the Upper Guinea forest, West Africa

open access: yesEcology and Society, 2016
The cultural valuation of biodiversity has taken on renewed importance over the last two decades as the ecosystem services framework has become widely adopted.
James A. Fraser   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Open access principles and practices benefit conservation

open access: yesConservation Letters, 2019
Open access is often contentious in the scientific community, but its implications for conservation are under‐discussed or omitted entirely from scientific discourse.
Jesse M. Alston
doaj   +1 more source

Conservation status of New Zealand freshwater invertebrates, 2013 [PDF]

open access: yes, 2014
The conservation status of 644 freshwater invertebrate taxa, across five Phyla, 28 Orders and 75 Families, was assessed using the New Zealand Threat Classification System (NZTCS) criteria.
Collier, Kevin J.   +6 more
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Non-Invasive Preservation Assessment of Archaeological Animal Bones by Complementary Imaging Techniques

open access: yesHeritage
The preservation of archaeological bone is of great importance for both archaeological and conservation science studies. Traditional methods of preservation assessment, such as attenuated total reflectance Fourier transform infrared spectroscopy (ATR ...
Chloe Pearce   +5 more
doaj   +1 more source

The role of educators in promoting collaborative research

open access: yesCeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2017
This paper examines some of the current science policy paradigms set at international level to promote open science and participatory research, and discusses how key factors necessary for successful collaboration can usefully contribute to the training ...
Stavroula Golfomitsou   +2 more
doaj   +1 more source

Conservation Science and Practice

open access: yes, 2013
We agree with Laurance et al. (2012) that conservation can gain when scientists and practitioners share perspectives. We suggest, however, that they already do.
Buckley, Ralf   +4 more
core   +1 more source

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