Results 61 to 70 of about 28,629,234 (254)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Trust in science: a critical review of the complex interactions between credibility and trust associated with conservation science

Frontiers in Communication
The credibility enjoyed by natural science and scientists during most of the 20th Century has been challenged in the 21st Century. Philosophers of science have noted waning trust in science as an appropriate foundation for sociopolitical decisions ...
Cristi Choat Horton, Rachel Lane, Tarla R. Peterson   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Weathering of Granite-Based Stone Cultural Heritage: A Multianalytical Review of Mineralogical Alteration, Microcracking, and Decay Patterns

Heritage
Granite is a major lithology of stone-built cultural heritage across East Asia, the Iberian Peninsula, the Indian subcontinent, Egypt and Italy. Long regarded as durable, it nonetheless undergoes mineralogical, microstructural and macroscopic alteration ...
Seungyeol Lee
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Decades of IUCN recommendations for biocontrol of invasive pest on the Guam cycad: you can lead policy-makers to conservation proposals but you cannot make them follow

Journal of Threatened Taxa
Guam’s cycad known as Cycas micronesica has been threatened by a coalition of invasive herbivore species, and the armored scale Aulacaspis yasumatsui has emerged as the primary threat.
Thomas E. Marler, Anders J. Lindström, L. Irene Terry, Benjamin E. Deloso   +3 more
doaj   +1 more source

Impact!: Conservation and Environmental Science Center for Southern New Jersey

, 1969
This brochure describes the history and goals of the Conservation and Environment Science Center (CESC) for Southern New ...

core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Fine‐tuning established morphometric models through citizen science data

Conservation Science and Practice
For globally threatened species, patchy data pose challenges in both establishing historical baselines and assessing current distributions. In the case of sawfishes, much previous research has relied on amputated trophy rostra or historical photographs ...
Veronika N. Biskis, Kathy A. Townsend, David L. Morgan, Karissa O. Lear, Bonnie J. Holmes, Barbara E. Wueringer   +5 more
doaj   +1 more source

Culturally Relevant STEM (CReST): An Integrated Support Curriculum for High School Chemistry and World History

Education Sciences
Convergence education, driven by compelling or complex socio-scientific problems, is an approach to bring cultural relevance into secondary STEM education.
James K. Ferri, Rachel Sparks White
doaj   +1 more source