Results 81 to 90 of about 1,820,994 (309)

Saving our species [PDF]

open access: yes
Science is vital to our conservation management. Our ecologists work hand-in-hand with land managers to plan and deliver effective conservation management for Australia’s species.
Jim Radford
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Summary Report: Project Terra Research Meeting [PDF]

open access: yes, 2000
Developing the conservation of earthen architectural Heritage -- as a science, a field of study, a professional practice, and a social endeavor -- is the overall objective of Project ...

core  

Semiclassical Time Evolution of the Holes from Luttinger Hamiltonian

open access: yes, 2004
We study the semi-classical motion of holes by exact numerical solution of the Luttinger model. The trajectories obtained for the heavy and light holes agree well with the higher order corrections to the abelian and the non-abelian adiabatic theories in ...
Jiang, Z. F.   +3 more
core   +1 more source

Age and growth of Zapteryx brevirostris (Elasmobranchii: Rhinobatidae) in southern Brazil [PDF]

open access: yes, 2018
Age and growth studies are fundamental to successful fisheries management. Zapteryx brevirostris (Muller & Henle, 1841) is distributed off the Brazilian continental shelf and this species is assessed as "Vulnerable" in the Red List of the International ...
Carmo, Wanessa P. D.   +2 more
core   +4 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Climate change, forest conservation and science: A case study of New Zealand, 1860s-1920 [PDF]

open access: yes, 2009
To most of its European settlers, New Zealand was a land blessed by Providence. A temperate climate and year-round rainfall, easy availability of land and myriad work opportunities attracted many to the new colony.
Beattie, James John
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Year 1 report for ‘Conserving Texas Biodiversity: Status, Trends, and Conservation Planning for Fishes of Greatest Conservation Need’ [PDF]

open access: yes, 2015
State Wildlife Grant Program, grant TX T-106-1 (CFDA# 15.634), Contract No. 459125 UTA14-001402Substantive progress was made on all major Project Activities in this first year: Activity 1.
Casarez, Melissa   +4 more
core   +1 more source

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