Results 131 to 140 of about 5,247,859 (404)

Illegal, Unreported and Unregulated (IUU) Fishing: A Whitepaper [PDF]

open access: yes, 2015
Illegal, unregulated and unreported (IUU) fishing refers to fishing activities that do not comply with regional, national, or international fisheries conservation or management measures.
Bernd Cordes
core  

Evaluating the potential for the environmentally sustainable control of foot and mouth disease in Sub-Saharan Africa [PDF]

open access: yes, 2013
Strategies to control transboundary diseases have in the past generated unintended negative consequences for both the environment and local human populations.
A Caron   +55 more
core   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Evaluating the Status of Lost, Found and Sighted Non-Native Pet Bird Species in South Africa

open access: yesDiversity
The global increase in the pet trade and ownership of pet birds has heightened the introduction of emerging invasive vertebrate species. We analyzed online databases of lost, found, and sighted non-native pet bird reports in South Africa to evaluate non ...
Tinyiko C. Shivambu   +5 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Florida’s Bee Species of Greatest Conservation Need

open access: yesEDIS
Twenty five bee species are listed as Species of Greatest Conservation Need in the Florida State Wildlife Action Plan. A diverse and abundant wild bee community is often more effective at pollination than honey bees, but wild bee abundance and diversity
Walker Bensch, Rachel Mallinger
doaj   +1 more source

Update of Ichthyofauna and its Conservation Status in the Aghien Lagoon, Côte d’Ivoire

open access: yesCroatian Journal of Fisheries, 2019
This study focused on the diversity of fish fauna, its conservation status and its vulnerability in the Aghien freshwater lagoon (southeast of Côte d'Ivoire).
Konan Koffi Félix   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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