Results 81 to 90 of about 345,037 (258)

Florida’s Bee Species of Greatest Conservation Need

EDIS
Twenty five bee species are listed as Species of Greatest Conservation Need in the Florida State Wildlife Action Plan. A diverse and abundant wild bee community is often more effective at pollination than honey bees, but wild bee abundance and diversity
Walker Bensch, Rachel Mallinger
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

(Clusiaceae), a new record for Bhutan and its ethnopharmacological potential

Journal of Threatened Taxa
Garcinia pedunculata Roxb. ex Buch.-Ham. is reported here for the first time in Bhutan, specifically from Zhemgang District. The species holds significant local value; its fruits are consumed as food and used as dye mordants, as well as in traditional ...
Jigme Wangchuk, Ugyen Dorji, Sherub Dorji, Yograj `Chhetri, Tsethup Tshering   +4 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Interspecific Habitat Suitability of Four Southeast Asian Spiny Climbing Palms (Korthalsia) Through Species Distribution Modeling

Plants
Rattans of the genus Korthalsia are ecologically and economically important non-timber forest resources in Southeast Asia, yet their conservation is limited by knowledge of species-specific distribution patterns and environmental constraints.
Tushar Andriyas, Nisa Leksungnoen, Suwimon Uthairatsamee, Chatchai Ngernsaengsaruay, Nisachol Pungtambol, Pichet Chanton, Nittaya Mianmit, Wirongrong Duangjai, Buapan Puangsin, Phruet Racharak   +9 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Current conservation status and potential distribution under climate change of Michelia lacei, a Plant Species with Extremely Small Populations in Yunnan, China

Oryx
Michelia lacei W.W. Smith, a magnolia species categorized as Endangered on the IUCN Red List, is subject to severe disturbance. We carried out field surveys and a review of literature records to present a detailed description of the current status of M ...
Yang Liu, Lei Cai, Weibang Sun
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Update of Ichthyofauna and its Conservation Status in the Aghien Lagoon, Côte d’Ivoire

Croatian Journal of Fisheries, 2019
This study focused on the diversity of fish fauna, its conservation status and its vulnerability in the Aghien freshwater lagoon (southeast of Côte d'Ivoire).
Konan Koffi Félix, Assi Sonan Romuald, Boussou Koffi Charles, Gourène Germain   +3 more
doaj   +1 more source