Results 91 to 100 of about 153,244 (285)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Defining 'Biodiversity'; Assessing Biodiversity [PDF]
, 2001 This paper analyzes the concept of biodiversity in conservation biology and assesses potential methods for its ...
Sarkar, Sahotra
core
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Conservation units: contributions to sustainable development [PDF]
, 2019 Bearing in mind that public use of Conservation Units has the role of boosting the local economy and promoting environmental awareness, this work aims to demonstrate that Conservation Units can be instruments of economic development for the region in ...
Spanholi, Maira Luiza +1 more
core
A Remotely Controlled Calibrator for Chemical Pollutant Measuring-Units [PDF]
, 2007 The increasing diffusion of pollutant measuring units, which are installed over wide areas, along with the short calibration interval of several sensors for pollutant quantities, requires new calibration infrastructures to be developed.
Carullo, Alessio +2 more
core +1 more source
Conservation Series, Unit V: Wild Flower Conservation
The American Biology Teacher, 1945 The real problems in wild flower preservation are much misunderstood by most of the general public and are often overlooked by the majority of teachers and well-meaning conservationists. The objectives of most of the workers have been largelv of a sentimental and aesthetic nature rather than following lines of any practical value. Some have gone so far
openaire +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Vulnerability of dynamic genetic conservation units of forest trees in Europe to climate change [PDF]
, 2014 A transnational network of genetic conservation units for forest trees was recently documented in Europe aiming at the conservation of evolutionary processes and the adaptive potential of natural or man-made tree populations. In this study, we quantified
Falk, Wolfgang +17 more
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source